Magnesium 用于高血压

B 证据至少一项随机试验支持这一结论，结果基本一致。

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

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结论

Key Study Findings

Review

Dietary supplements and prevention of preeclampsia.

Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction 效果: ~50% risk reduction None

研究人群: Pregnant women with low calcium intake

Case Reports 13.0 weeks

A case report of Gitelman syndrome in children.

Dose: 3 g vs: None Outcome: pain reduction 效果: None None

研究人群: Hypokalemia

Review

Nutritional prevention of cognitive decline and dementia.

Dose: None vs: None Outcome: Cognitive decline prevention 效果: None None

研究人群: Older adults at risk of cognitive decline

Systematic Review

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on …

Dose: varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements vs: Placebo 效果: None None

Review

Prevention of hypokalemia caused by diuretics.

Dose: None vs: None Outcome: mineral status 效果: None None

研究人群: hypertensive patients

Randomized Controlled Trial n=48 26.0 weeks

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for …

Dose: 100 mg/d vs: control group Outcome: blood pressure 效果: None None

研究人群: hypertensive patients

Key Statistics

研究数量

2028

受试者

↑

Positive

等级

Referenced Papers

Dietary supplements and prevention of preeclampsia. Review

Hypertension research : … 2025 10 次引用

A case report of Gitelman syndrome in children. Case Report

Medicine 2023

Nutritional prevention of cognitive decline and dementia. Review

Acta bio-medica : … 2018 103 次引用

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … Systematic Review

JBI database of … 2017 38 次引用

Prevention of hypokalemia caused by diuretics. Review

Heart disease and … 1994

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … RCT

European journal of … 1986 22 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:: 310-420 mg/day
bloodpressuresupport:: 300-500 mg/day
cardiovascularsupport:: 300-400 mg/day elemental magnesium

上限： 350 mg/day from supplements only (no UL for food magnesium)

研究中使用的剂量

剂量	持续时间	效果	N
500 mg daily	--	Positive	--
3 g	13.0 weeks	Mixed	--
None	--	Mixed	--
varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements	--	Mixed	--
None	--	Mixed	--
100 mg/d	26.0 weeks	Mixed	48

最佳服用时间： With meals to reduce GI side effects; evening dosing may support sleep

Safety & Side Effects

已报告的副作用

⚠ Diarrhea (especially magnesium oxide and citrate)
⚠ Nausea
⚠ Abdominal cramping
⚠ Excessive doses may cause hypotension or cardiac depression

已知相互作用

● Bisphosphonates (reduced absorption — separate by 2 hours)
● Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
● Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
● Proton pump inhibitors (long-term use may cause hypomagnesemia)

可耐受最高摄入量： 350 mg/day from supplements only (no UL for food magnesium)

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Magnesium help with 高血压?

Based on 34 studies with 2,028 participants, there is moderate evidence from clinical studies that Magnesium may support 高血压 management. Our evidence grade is B (Good Evidence).

How much Magnesium should I take for 高血压?

Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Magnesium?

Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Magnesium and 高血压?

We rate the evidence as Grade B (Good Evidence). This rating is based on 34 peer-reviewed studies with 2,028 total participants. The overall direction of effect is positive.

其他成分用于高血压

Beetroot Extract A Garlic A Potassium B Quercetin B Grape Seed Extract B Coenzyme Q10 (CoQ10) B

Magnesium 用于其他健康状况

心律失常 B 冠状动脉疾病（CAD） C

快速结论

Evidence Strength72%

High confidence

研究分析

RCT (1)Meta (0)Other (33)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于高血压

了解更多

References

[1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
[2] Jing Ying et al.. Medicine (Baltimore). 2023. A case report of Gitelman syndrome in children. doi:10.1097/MD.0000000000033509 PubMed
[3] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed
[4] Delia McCabe et al.. JBI Database System Rev Implement Rep. 2017. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … doi:10.11124/JBISRIR-2016-002965 PubMed
[5] E Bourke et al.. Heart Dis Stroke. 1994. Prevention of hypokalemia caused by diuretics. PubMed
[6] T Dyckner et al.. Eur J Clin Pharmacol. 1986. Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … doi:10.1007/BF00542411 PubMed

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Magnesium 用于 高血压

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结论

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

常用剂量

研究中使用的剂量

Safety & Side Effects

已报告的副作用

已知相互作用

Frequently Asked Questions

Related Evidence

其他成分用于 高血压

Magnesium 用于其他健康状况

References

Magnesium 用于高血压

其他成分用于高血压