健康状况

18 基于循证研究的健康状况与补充剂信息

Explore health conditions with evidence-graded supplement recommendations. Each condition page ranks ingredients by the strength of clinical research supporting them.

How We Grade Evidence

每个健康状况页面按临床证据强度对补充剂成分进行排序。以下是各等级的含义：

Strong Evidence

Multiple randomized controlled trials (RCTs) or meta-analyses with consistent positive results and large sample sizes.

Good Evidence

At least one RCT with mostly consistent results across studies. Evidence suggests benefit but more research may be needed.

Some Evidence

Small studies or observational data with some positive signals. Promising but insufficient for strong recommendations.

Very Early Research

In vitro studies, case reports, or pilot studies only. Early-stage research that requires clinical validation.

代谢综合征（心血管方面）

34% of US adults; prevalence increasing globally parallel to obesity epidemic

Central obesity (waist >40 inches men, >35 inches women) Elevated fasting glucose (>100 mg/dL) Elevated triglycerides (>150 mg/dL) +2

内皮功能障碍

Present in virtually all patients with cardiovascular risk factors

Usually asymptomatic (subclinical) Reduced exercise tolerance Erectile dysfunction +1

冠状动脉疾病（CAD）

20.5 million US adults; leading cause of death globally (17.9 million deaths/year)

Angina pectoris (chest pain/pressure with exertion) Shortness of breath Fatigue +1

动脉僵硬度

Universal with aging; 20-30% of adults >60 have PWV >10 m/s

Usually asymptomatic Contributes to isolated systolic hypertension Widened pulse pressure +1

动脉粥样硬化

Subclinical atherosclerosis present in >50% of adults over 40

Often asymptomatic until advanced Angina Claudication +1

外周动脉疾病（PAD）

8.5 million US adults; 12-20% of adults >60 years

Intermittent claudication (leg pain with walking) Numbness/weakness in legs Cold legs/feet +2

心力衰竭

6.7 million US adults; prevalence increases with age (10% in adults >65)

Dyspnea (exertional and at rest) Orthopnea Paroxysmal nocturnal dyspnea +3

心律失常

Atrial fibrillation: 33.5 million worldwide; PVCs: present in 75% of healthy adults

Palpitations Skipped beats Racing heart +3

心悸

Very common — up to 16% of primary care visits cite palpitations

Awareness of heartbeat Fluttering or pounding sensation Skipping beats +3

心肌梗死后恢复

~805,000 MIs/year in the US; 200,000 are recurrent events

Fatigue Reduced exercise tolerance Chest discomfort +2

心血管炎症

hs-CRP >2 mg/L present in ~25% of US adults

Usually measured by lab markers (hs-CRP, IL-6, TNF-alpha) Associated with accelerated atherosclerosis Plaque instability

氧化应激（心血管）

Measurable biomarkers elevated in >80% of CVD patients

Subclinical; contributes to accelerated cardiovascular aging Associated with endothelial dysfunction Arterial stiffness +1

血液循环不良

Symptoms of poor circulation affect 15-20% of adults >50

Cold hands/feet Numbness/tingling in extremities Slow wound healing +3

静脉曲张（慢性静脉功能不全）

20-30% of adults; higher in women (2:1 ratio)

Visible dilated veins Leg heaviness/aching Swelling (worse with standing) +3

高同型半胱氨酸血症

5-10% of general population; up to 30-40% of elderly

Usually asymptomatic Associated with premature atherosclerosis Thromboembolism

高甘油三酯血症

25-30% of US adults have elevated triglycerides (>=150 mg/dL)

Usually asymptomatic Very high levels (>500): eruptive xanthomas Lipemia retinalis +1

高胆固醇血症（高脂血症）

38% of US adults have total cholesterol >=200 mg/dL; 12% have LDL >=160 mg/dL

Usually asymptomatic Xanthomas (tendon/skin deposits) in severe cases Corneal arcus +1

高血压

47% of US adults (116 million); ~1.28 billion adults worldwide

Often asymptomatic ('silent killer') Severe: headache, shortness of breath, nosebleeds Chest pain +2

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