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Magnesium 用于 Coronary Artery Disease (CAD)

C

Prospective cohorts show 22% lower CHD risk with higher magnesium intake. Interventional data is limited. Mechanistic rationale is strong (anti-inflammatory, anti-arrhythmic effects).

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            C

        

        

            
结论

            
            
Prospective cohorts show 22% lower CHD risk with higher magnesium intake. Interventional data is limited. Mechanistic rationale is strong (anti-inflammatory, anti-arrhythmic effects).

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
5

        
研究数量

    

    

        
350

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
等级

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
310-420 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
300-500 mg/day

                    

                    
                    

                        
cardiovascularsupport:

                        
300-400 mg/day elemental magnesium

                    

                    
                

                
                

                    上限： 350 mg/day from supplements only (no UL for food magnesium)
                

                
            

            

            

            
            

                最佳服用时间： With meals to reduce GI side effects; evening dosing may support sleep
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Diarrhea (especially magnesium oxide and citrate)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea
                        
    • 
                        
                        
  • 
                            ⚠
                            Abdominal cramping
                        
    • 
                        
                        
  • 
                            ⚠
                            Excessive doses may cause hypotension or cardiac depression
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Bisphosphonates (reduced absorption — separate by 2 hours)
                        
    • 
                        
                        
  • 
                            ●
                            Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
                        
    • 
                        
                        
  • 
                            ●
                            Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
                        
    • 
                        
                        
  • 
                            ●
                            Proton pump inhibitors (long-term use may cause hypomagnesemia)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： 350 mg/day from supplements only (no UL for food magnesium)
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Magnesium help with Coronary Artery Disease (CAD)?
            
        
        

            Based on 5 studies with 350 participants, there is limited but promising evidence that Magnesium may support Coronary Artery Disease (CAD) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Magnesium should I take for Coronary Artery Disease (CAD)?
            
        
        

            Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Magnesium?
            
        
        

            Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Magnesium and Coronary Artery Disease (CAD)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
其他成分用于 Coronary Artery Disease (CAD)

                    

                        
                        
                            Omega-3 Fatty Acids (EPA/DHA)
                            B

                        
                        
                        
                            Folate (Vitamin B9)
                            C

                        
                        
                        
                            Selenium
                            C

                        
                        
                    

                

                

                
                
                
            

        

        

    


    
    












    

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