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HeartCited

Magnesium
Magnesium

mineral

别名: Magnesium Glycinate, Magnesium Citrate, Magnesium Taurate, Magnesium L-Threonate, Magnesium Oxide

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About





            

                
Magnesium is an essential cofactor for over 300 enzymatic reactions including those regulating vascular tone. It acts as a natural calcium channel blocker, relaxing vascular smooth muscle and reducing peripheral resistance. A 2016 meta-analysis of 34 RCTs found magnesium supplementation significantly reduced systolic blood pressure by 2.0 mmHg and diastolic by 1.78 mmHg. Approximately 50% of the US population consumes less than the EAR for magnesium.

            

        

        

        
        
        

            

  
How It Works





            

                
Essential cofactor for >300 enzymatic reactions regulating vascular tone; acts as a natural calcium channel blocker relaxing vascular smooth muscle; modulates cardiac electrical activity by stabilizing potassium and calcium channels (anti-arrhythmic); supports endothelial nitric oxide production; regulates Na+/K+-ATPase critical for cardiac membrane potential.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Blood Pressure (Hypertension)
                                    
                                
                                
                                    B

                                
                                
                                    34
                                
                                
                                    2028
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                            

                                
                                    
                                        Cardiac Arrhythmia
                                    
                                
                                
                                    B

                                
                                
                                    8
                                
                                
                                    500
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                            

                                
                                    
                                        Coronary Artery Disease (CAD)
                                    
                                
                                
                                    C

                                
                                
                                    5
                                
                                
                                    350
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Diarrhea (especially magnesium oxide and citrate)
                
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                    Nausea
                
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                    Abdominal cramping
                
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                    Excessive doses may cause hypotension or cardiac depression
                
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Drug & Supplement Interactions





            
    
                
                
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                    Bisphosphonates (reduced absorption — separate by 2 hours)
                
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                    Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
                
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                    Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
                
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                    Proton pump inhibitors (long-term use may cause hypomagnesemia)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Potassium
                    
                
                
                
                    Calcium
                    
                
                
                
                    Selenium
                    
                
                
            

        

        
    


    
    












    

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