Magnesium para High Blood Pressure (Hypertension)

B Evidencia Al menos un ensayo aleatorizado lo respalda, con resultados mayoritariamente consistentes.

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

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Conclusión

Key Study Findings

Review

Dietary supplements and prevention of preeclampsia.

Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction Efecto: ~50% risk reduction None

Población: Pregnant women with low calcium intake

Case Reports 13.0 weeks

A case report of Gitelman syndrome in children.

Dose: 3 g vs: None Outcome: pain reduction Efecto: None None

Población: Hypokalemia

Review

Nutritional prevention of cognitive decline and dementia.

Dose: None vs: None Outcome: Cognitive decline prevention Efecto: None None

Población: Older adults at risk of cognitive decline

Systematic Review

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on …

Dose: varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements vs: Placebo Efecto: None None

Review

Prevention of hypokalemia caused by diuretics.

Dose: None vs: None Outcome: mineral status Efecto: None None

Población: hypertensive patients

Randomized Controlled Trial n=48 26.0 weeks

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for …

Dose: 100 mg/d vs: control group Outcome: blood pressure Efecto: None None

Población: hypertensive patients

Key Statistics

Estudios

2028

Participantes

↑

Positive

Calificación

Referenced Papers

Dietary supplements and prevention of preeclampsia. Review

Hypertension research : … 2025 10 citas

A case report of Gitelman syndrome in children. Case Report

Medicine 2023

Nutritional prevention of cognitive decline and dementia. Review

Acta bio-medica : … 2018 103 citas

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … Systematic Review

JBI database of … 2017 38 citas

Prevention of hypokalemia caused by diuretics. Review

Heart disease and … 1994

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … RCT

European journal of … 1986 22 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

general:: 310-420 mg/day
bloodpressuresupport:: 300-500 mg/day
cardiovascularsupport:: 300-400 mg/day elemental magnesium

Límite superior: 350 mg/day from supplements only (no UL for food magnesium)

Dosificaciones estudiadas en la investigación

Dosificación	Duración	Efecto	N
500 mg daily	--	Positive	--
3 g	13.0 weeks	Mixed	--
None	--	Mixed	--
varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements	--	Mixed	--
None	--	Mixed	--
100 mg/d	26.0 weeks	Mixed	48

Mejor momento para tomar: With meals to reduce GI side effects; evening dosing may support sleep

Safety & Side Effects

Efectos secundarios reportados

⚠ Diarrhea (especially magnesium oxide and citrate)
⚠ Nausea
⚠ Abdominal cramping
⚠ Excessive doses may cause hypotension or cardiac depression

Interacciones conocidas

● Bisphosphonates (reduced absorption — separate by 2 hours)
● Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
● Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
● Proton pump inhibitors (long-term use may cause hypomagnesemia)

Ingesta máxima tolerable: 350 mg/day from supplements only (no UL for food magnesium)

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Magnesium help with High Blood Pressure (Hypertension)?

Based on 34 studies with 2,028 participants, there is moderate evidence from clinical studies that Magnesium may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).

How much Magnesium should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Magnesium?

Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Magnesium and High Blood Pressure (Hypertension)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 34 peer-reviewed studies with 2,028 total participants. The overall direction of effect is positive.

Otros ingredientes para High Blood Pressure (Hypertension)

Beetroot Extract A Garlic A Potassium B Quercetin B Grape Seed Extract B Coenzyme Q10 (CoQ10) B

Magnesium para otras condiciones

Cardiac Arrhythmia B Coronary Artery Disease (CAD) C

Veredicto rápido

Evidence Strength72%

High confidence

Desglose de estudios

RCT (1)Meta (0)Other (33)

Comparar alternativas

Vea cómo se comparan otros ingredientes para esta condición.

Ver todos los ingredientes para High Blood Pressure (Hypertension)

Más información

References

[1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
[2] Jing Ying et al.. Medicine (Baltimore). 2023. A case report of Gitelman syndrome in children. doi:10.1097/MD.0000000000033509 PubMed
[3] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed
[4] Delia McCabe et al.. JBI Database System Rev Implement Rep. 2017. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … doi:10.11124/JBISRIR-2016-002965 PubMed
[5] E Bourke et al.. Heart Dis Stroke. 1994. Prevention of hypokalemia caused by diuretics. PubMed
[6] T Dyckner et al.. Eur J Clin Pharmacol. 1986. Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … doi:10.1007/BF00542411 PubMed

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.

Magnesium para High Blood Pressure (Hypertension)

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Conclusión

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Dosificaciones de uso común

Dosificaciones estudiadas en la investigación

Safety & Side Effects

Efectos secundarios reportados

Interacciones conocidas

Frequently Asked Questions

Related Evidence

Otros ingredientes para High Blood Pressure (Hypertension)

Magnesium para otras condiciones

References