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Magnesium pour High Blood Pressure (Hypertension)

B Preuves Au moins un essai randomisé le soutient, avec des résultats globalement concordants.

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

B

En conclusion

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction Effet: ~50% risk reduction

Population: Pregnant women with low calcium intake

Case Reports 13.0 weeks
A case report of Gitelman syndrome in children.
Dose: 3 g Outcome: pain reduction

Population: Hypokalemia

Systematic Review
The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on …
Dose: varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements vs: Placebo
Randomized Controlled Trial n=48 26.0 weeks
Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for …
Dose: 100 mg/d vs: control group Outcome: blood pressure

Population: hypertensive patients

Key Statistics

34

Études

2028

Participants

↑

Positive

B

Note

Referenced Papers

Dietary supplements and prevention of preeclampsia. Review
Hypertension research : … 2025 10 citations
A case report of Gitelman syndrome in children. Case Report
Medicine 2023
Nutritional prevention of cognitive decline and dementia. Review
Acta bio-medica : … 2018 103 citations
The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … Systematic Review
JBI database of … 2017 38 citations
Prevention of hypokalemia caused by diuretics. Review
Heart disease and … 1994
Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … RCT
European journal of … 1986 22 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:
310-420 mg/day
bloodpressuresupport:
300-500 mg/day
cardiovascularsupport:
300-400 mg/day elemental magnesium

Limite supérieure : 350 mg/day from supplements only (no UL for food magnesium)

Posologies étudiées dans la recherche

Posologie Durée Effet N
500 mg daily -- Positive --
3 g 13.0 weeks Mixed --
varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements -- Mixed --
100 mg/d 26.0 weeks Mixed 48

Moment optimal de prise : With meals to reduce GI side effects; evening dosing may support sleep

Safety & Side Effects

Effets indésirables signalés

  • ⚠ Diarrhea (especially magnesium oxide and citrate)
  • ⚠ Nausea
  • ⚠ Abdominal cramping
  • ⚠ Excessive doses may cause hypotension or cardiac depression

Interactions connues

  • ● Bisphosphonates (reduced absorption — separate by 2 hours)
  • ● Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
  • ● Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
  • ● Proton pump inhibitors (long-term use may cause hypomagnesemia)

Apport maximal tolérable : 350 mg/day from supplements only (no UL for food magnesium)

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Magnesium help with High Blood Pressure (Hypertension)?
Based on 34 studies with 2,028 participants, there is moderate evidence from clinical studies that Magnesium may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Magnesium should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Magnesium?
Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Magnesium and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 34 peer-reviewed studies with 2,028 total participants. The overall direction of effect is positive.

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References

  
    
    
    
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      Takafumi Ushida et al..
      Hypertens Res.
      2025.
      Dietary supplements and prevention of preeclampsia.
      doi:10.1038/s41440-025-02144-9
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Jing Ying et al..
      Medicine (Baltimore).
      2023.
      A case report of Gitelman syndrome in children.
      doi:10.1097/MD.0000000000033509
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Ligia J Dominguez et al..
      Acta Biomed.
      2018.
      Nutritional prevention of cognitive decline and dementia.
      doi:10.23750/abm.v89i2.7401
      PubMed
    
    4. 
    
    
  4. 
      [4]
      Delia McCabe et al..
      JBI Database System Rev Implement Rep.
      2017.
      The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a …
      doi:10.11124/JBISRIR-2016-002965
      PubMed
    
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      E Bourke et al..
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      Prevention of hypokalemia caused by diuretics.
      
      PubMed
    
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      [6]
      T Dyckner et al..
      Eur J Clin Pharmacol.
      1986.
      Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial …
      doi:10.1007/BF00542411
      PubMed
    
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        Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.