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Magnesium для High Blood Pressure (Hypertension)

B Доказательства По меньшей мере одно рандомизированное исследование подтверждает это, с в целом согласованными результатами.

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

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B

Итог

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily или: Placebo Outcome: Preeclampsia risk reduction Эффект: ~50% risk reduction None

Популяция: Pregnant women with low calcium intake

Case Reports 13.0 weeks
A case report of Gitelman syndrome in children.
Dose: 3 g или: None Outcome: pain reduction Эффект: None None

Популяция: Hypokalemia

Review
Nutritional prevention of cognitive decline and dementia.
Dose: None или: None Outcome: Cognitive decline prevention Эффект: None None

Популяция: Older adults at risk of cognitive decline

Systematic Review
The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on …
Dose: varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements или: Placebo Эффект: None None
Review
Prevention of hypokalemia caused by diuretics.
Dose: None или: None Outcome: mineral status Эффект: None None

Популяция: hypertensive patients

Randomized Controlled Trial n=48 26.0 weeks
Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for …
Dose: 100 mg/d или: control group Outcome: blood pressure Эффект: None None

Популяция: hypertensive patients

Key Statistics

34

Исследования

2028

Участники

Positive

B

Оценка

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
310-420 mg/day
bloodpressuresupport:
300-500 mg/day
cardiovascularsupport:
300-400 mg/day elemental magnesium

Верхний предел: 350 mg/day from supplements only (no UL for food magnesium)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
500 mg daily -- Positive --
3 g 13.0 weeks Mixed --
None -- Mixed --
varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements -- Mixed --
None -- Mixed --
100 mg/d 26.0 weeks Mixed 48

Лучшее время приёма: With meals to reduce GI side effects; evening dosing may support sleep

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Diarrhea (especially magnesium oxide and citrate)
  • Nausea
  • Abdominal cramping
  • Excessive doses may cause hypotension or cardiac depression

Известные взаимодействия

  • Bisphosphonates (reduced absorption — separate by 2 hours)
  • Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
  • Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
  • Proton pump inhibitors (long-term use may cause hypomagnesemia)

Допустимый верхний уровень потребления: 350 mg/day from supplements only (no UL for food magnesium)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Magnesium help with High Blood Pressure (Hypertension)?
Based on 34 studies with 2,028 participants, there is moderate evidence from clinical studies that Magnesium may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Magnesium should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Magnesium?
Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Magnesium and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 34 peer-reviewed studies with 2,028 total participants. The overall direction of effect is positive.

Другие ингредиенты для High Blood Pressure (Hypertension)

Magnesium для других состояний

References

  1. [1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
  2. [2] Jing Ying et al.. Medicine (Baltimore). 2023. A case report of Gitelman syndrome in children. doi:10.1097/MD.0000000000033509 PubMed
  3. [3] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed
  4. [4] Delia McCabe et al.. JBI Database System Rev Implement Rep. 2017. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … doi:10.11124/JBISRIR-2016-002965 PubMed
  5. [5] E Bourke et al.. Heart Dis Stroke. 1994. Prevention of hypokalemia caused by diuretics. PubMed
  6. [6] T Dyckner et al.. Eur J Clin Pharmacol. 1986. Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … doi:10.1007/BF00542411 PubMed

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