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Magnesium для Coronary Artery Disease (CAD)

C Доказательства Доказательства ограничены небольшими исследованиями, однако имеются некоторые положительные сигналы.

Prospective cohorts show 22% lower CHD risk with higher magnesium intake. Interventional data is limited. Mechanistic rationale is strong (anti-inflammatory, anti-arrhythmic effects).

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            C

        

        

            
Итог

            
            
Prospective cohorts show 22% lower CHD risk with higher magnesium intake. Interventional data is limited. Mechanistic rationale is strong (anti-inflammatory, anti-arrhythmic effects).

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                [Atrial fibrillation after coronary artery bypass surgery: possibilities of prevention].
            
            

                
                Dose: None
                
                
                или: None
                
                
                Outcome: mortality
                
                
                Эффект: None
                
                
                None
                
            

            
            
Популяция: heart failure patients

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
5

        
Исследования

    

    

        
350

        
Участники

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Оценка

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            [Atrial fibrillation after coronary artery bypass surgery: possibilities of prevention].
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Srpski arhiv za …
                        2012
                        
                        3 цитирований
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Часто используемые дозировки

                

                    
                    

                        
general:

                        
310-420 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
300-500 mg/day

                    

                    
                    

                        
cardiovascularsupport:

                        
300-400 mg/day elemental magnesium

                    

                    
                

                
                

                    Верхний предел: 350 mg/day from supplements only (no UL for food magnesium)
                

                
            

            

            
            

                
Дозировки, изученные в исследованиях

                

                    

                        
                            

                                Дозировка
                                Длительность
                                Эффект
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Лучшее время приёма: With meals to reduce GI side effects; evening dosing may support sleep
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Зарегистрированные побочные эффекты

                    
    
                        
                        
  • 
                            ⚠
                            Diarrhea (especially magnesium oxide and citrate)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea
                        
    • 
                        
                        
  • 
                            ⚠
                            Abdominal cramping
                        
    • 
                        
                        
  • 
                            ⚠
                            Excessive doses may cause hypotension or cardiac depression
                        
    • 
                        
                    

                

                

                
                

                    
Известные взаимодействия

                    
    
                        
                        
  • 
                            ●
                            Bisphosphonates (reduced absorption — separate by 2 hours)
                        
    • 
                        
                        
  • 
                            ●
                            Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
                        
    • 
                        
                        
  • 
                            ●
                            Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
                        
    • 
                        
                        
  • 
                            ●
                            Proton pump inhibitors (long-term use may cause hypomagnesemia)
                        
    • 
                        
                    

                

                

                
                

                    

                        Допустимый верхний уровень потребления: 350 mg/day from supplements only (no UL for food magnesium)
                    

                

                
            

            

                Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Magnesium help with Coronary Artery Disease (CAD)?
            
        
        

            Based on 5 studies with 350 participants, there is limited but promising evidence that Magnesium may support Coronary Artery Disease (CAD) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Magnesium should I take for Coronary Artery Disease (CAD)?
            
        
        

            Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Magnesium?
            
        
        

            Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Magnesium and Coronary Artery Disease (CAD)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                

                    
Другие ингредиенты для Coronary Artery Disease (CAD)

                    

                        
                        
                            Omega-3 Fatty Acids (EPA/DHA)
                            B

                        
                        
                        
                            Folate (Vitamin B9)
                            C

                        
                        
                        
                            Selenium
                            C

                        
                        
                    

                

                

                
                

                    
Magnesium для других состояний

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            B

                        
                        
                        
                            Cardiac Arrhythmia
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Biljana Obrenović-Kirćanski et al..
      Srp Arh Celok Lek.
      2012.
      [Atrial fibrillation after coronary artery bypass surgery: possibilities of prevention].
      doi:10.2298/sarh1208521o
      PubMed
    
    2. 
    
  















    

        Отказ от ответственности FDA:
        Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.