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Selenium для Coronary Artery Disease (CAD)

C Доказательства Доказательства ограничены небольшими исследованиями, однако имеются некоторые положительные сигналы.

SELECT trial was negative as monotherapy. KiSel-10 was positive in combination with CoQ10. U-shaped dose response — research suggests benefit only in deficient populations (serum <100 mcg/L).

C

Итог

SELECT trial was negative as monotherapy. KiSel-10 was positive in combination with CoQ10. U-shaped dose response — research suggests benefit only in deficient populations (serum <100 mcg/L).

Key Statistics

5

Исследования

10000

Участники

↔

Mixed

C

Оценка

Referenced Papers

Role of mercury toxicity in hypertension, cardiovascular disease, and stroke. Review
Journal of clinical … 2011 396 цитирований
Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway … Other
Neuro endocrinology letters 2011

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
55 mcg/day
cardiovascularantioxidant:
100-200 mcg/day

Верхний предел: 400 mcg/day (risk of selenosis above this level)

Лучшее время приёма: With meals

Safety & Side Effects

Зарегистрированные побочные эффекты

  • ⚠ Selenosis at high doses (garlic breath odor, hair/nail loss, nausea)
  • ⚠ GI discomfort at moderate-high doses
  • ⚠ Potential increased type 2 diabetes risk at high supplemental doses

Известные взаимодействия

  • ● Cisplatin and other chemotherapy drugs (may affect efficacy)
  • ● Statins (may enhance antioxidant effects)
  • ● CoQ10 (synergistic cardiovascular benefit — KiSel-10 combination)

Допустимый верхний уровень потребления: 400 mcg/day (risk of selenosis above this level)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Selenium help with Coronary Artery Disease (CAD)?
Based on 5 studies with 10,000 participants, there is limited but promising evidence that Selenium may support Coronary Artery Disease (CAD) management. Our evidence grade is C (Some Evidence).
How much Selenium should I take for Coronary Artery Disease (CAD)?
Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Selenium?
Reported side effects may include Selenosis at high doses (garlic breath odor, hair/nail loss, nausea), GI discomfort at moderate-high doses, Potential increased type 2 diabetes risk at high supplemental doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Selenium and Coronary Artery Disease (CAD)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 10,000 total participants. The overall direction of effect is mixed.

Другие ингредиенты для Coronary Artery Disease (CAD)

Omega-3 Fatty Acids (EPA/DHA) B Folate (Vitamin B9) C Magnesium C

Selenium для других состояний

Oxidative Stress (Cardiovascular) B

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References

  
    
    
    
  1. 
      [1]
      Mark C Houston.
      J Clin Hypertens (Greenwich).
      2011.
      Role of mercury toxicity in hypertension, cardiovascular disease, and stroke.
      doi:10.1111/j.1751-7176.2011.00489.x
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Michael Maes et al..
      Neuro Endocrinol Lett.
      2011.
      Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway …
      
      PubMed
    
    3. 
    
  















    

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