Skip to main content
HeartCited

Selenium untuk Coronary Artery Disease (CAD)

C Bukti Bukti terbatas dari studi kecil, namun beberapa sinyal positif ada.

SELECT trial was negative as monotherapy. KiSel-10 was positive in combination with CoQ10. U-shaped dose response — research suggests benefit only in deficient populations (serum <100 mcg/L).

C

Kesimpulan

SELECT trial was negative as monotherapy. KiSel-10 was positive in combination with CoQ10. U-shaped dose response — research suggests benefit only in deficient populations (serum <100 mcg/L).

Key Statistics

5

Studi

10000

Peserta

↔

Mixed

C

Peringkat

Referenced Papers

Role of mercury toxicity in hypertension, cardiovascular disease, and stroke. Review
Journal of clinical … 2011 396 sitasi
Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway … Other
Neuro endocrinology letters 2011

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:
55 mcg/day
cardiovascularantioxidant:
100-200 mcg/day

Batas atas: 400 mcg/day (risk of selenosis above this level)

Waktu terbaik diminum: With meals

Safety & Side Effects

Efek Samping yang Dilaporkan

  • ⚠ Selenosis at high doses (garlic breath odor, hair/nail loss, nausea)
  • ⚠ GI discomfort at moderate-high doses
  • ⚠ Potential increased type 2 diabetes risk at high supplemental doses

Interaksi yang Diketahui

  • ● Cisplatin and other chemotherapy drugs (may affect efficacy)
  • ● Statins (may enhance antioxidant effects)
  • ● CoQ10 (synergistic cardiovascular benefit — KiSel-10 combination)

Asupan atas yang dapat ditoleransi: 400 mcg/day (risk of selenosis above this level)

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Selenium help with Coronary Artery Disease (CAD)?
Based on 5 studies with 10,000 participants, there is limited but promising evidence that Selenium may support Coronary Artery Disease (CAD) management. Our evidence grade is C (Some Evidence).
How much Selenium should I take for Coronary Artery Disease (CAD)?
Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Selenium?
Reported side effects may include Selenosis at high doses (garlic breath odor, hair/nail loss, nausea), GI discomfort at moderate-high doses, Potential increased type 2 diabetes risk at high supplemental doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Selenium and Coronary Artery Disease (CAD)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 10,000 total participants. The overall direction of effect is mixed.

Selenium untuk kondisi lain

Oxidative Stress (Cardiovascular) B

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  










  
References

  
    
    
    
  1. 
      [1]
      Mark C Houston.
      J Clin Hypertens (Greenwich).
      2011.
      Role of mercury toxicity in hypertension, cardiovascular disease, and stroke.
      doi:10.1111/j.1751-7176.2011.00489.x
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Michael Maes et al..
      Neuro Endocrinol Lett.
      2011.
      Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway …
      
      PubMed
    
    3. 
    
  















    

        Penafian FDA:
        Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.