Garlic 用于 高血压
A 证据 多项大型临床试验一致显示出显著的益处。Meta-analysis of 12 RCTs: systolic -8.3 mmHg, diastolic -5.5 mmHg in hypertensives. Effect may be comparable to first-line antihypertensives. AGE at Heart trial showed 80% reduction in coronary calcium progression.
结论
Meta-analysis of 12 RCTs: systolic -8.3 mmHg, diastolic -5.5 mmHg in hypertensives. Effect may be comparable to first-line antihypertensives. AGE at Heart trial showed 80% reduction in coronary calcium progression.
Key Study Findings
研究人群: Older adults at risk of cognitive decline
研究人群: Women using herbal remedies
研究人群: Women
研究人群: hypertensive patients
Key Statistics
12
研究数量
550
受试者
Positive
等级
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- freshgarlic:
- 2-5g/day (1-2 cloves)
- agedgarlicextract:
- 600-1,200 mg/day
- allicinstandardized:
- 300-600 mg/day (5-12 mg allicin)
上限: Not formally established; GI discomfort and body odor limit high doses
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| Various herbs (black cohosh, chasteberry, dong quai, etc.) | -- | Mixed | -- |
| Various herbs used by women | -- | Mixed | -- |
| None | -- | Mixed | -- |
最佳服用时间: With meals to reduce GI side effects; enteric-coated tablets for allicin delivery
Safety & Side Effects
已报告的副作用
- ⚠ Body odor and bad breath (less with AGE)
- ⚠ Gastrointestinal discomfort (heartburn, nausea, gas)
- ⚠ Increased bleeding risk
- ⚠ Allergic reactions (rare)
已知相互作用
- ● Anticoagulants (increased bleeding risk — discontinue 7 days before surgery)
- ● Antiplatelet drugs (additive antiplatelet effect)
- ● HIV protease inhibitors (saquinavir — reduced levels)
- ● CYP3A4 substrates (may alter metabolism)
- ● Blood pressure medications (additive hypotensive effect)
可耐受最高摄入量: Not formally established; GI discomfort and body odor limit high doses
在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Garlic help with 高血压?
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How strong is the evidence for Garlic and 高血压?
Related Evidence
References
- [1] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed
- [2] Bonnie J Tesch. Am J Obstet Gynecol. 2003. Herbs commonly used by women: an evidence-based review. doi:10.1067/mob.2003.402 PubMed
- [3] Bonnie J Tesch. Dis Mon. 2002. Herbs commonly used by women: an evidence-based review. PubMed
- [4] T B Klepser et al.. Am J Health Syst Pharm. 1999. Unsafe and potentially safe herbal therapies. doi:10.1093/ajhp/56.2.125 PubMed
FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。