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HeartCited

Grape Seed Extract 用于 High Blood Pressure (Hypertension)

B

Meta-analysis of 16 RCTs: systolic -6.08 mmHg. Greater effect in younger (<50) and obese participants. OPC standardization important for consistent results.

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B

结论

Meta-analysis of 16 RCTs: systolic -6.08 mmHg. Greater effect in younger (<50) and obese participants. OPC standardization important for consistent results.

Key Statistics

16

研究数量

810

受试者

Positive

B

等级

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:
100-300 mg/day
bloodpressuresupport:
150-300 mg/day standardized to 95% OPCs

上限: Not formally established; up to 600 mg/day used in clinical trials

最佳服用时间: With or without food

Safety & Side Effects

已报告的副作用

  • Generally well-tolerated
  • Mild headache (rare)
  • Dizziness (rare)
  • Nausea (rare)

已知相互作用

  • Anticoagulants (may increase bleeding risk)
  • Blood pressure medications (additive hypotensive effect)
  • Iron supplements (tannins may reduce iron absorption)

可耐受最高摄入量: Not formally established; up to 600 mg/day used in clinical trials

在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Grape Seed Extract help with High Blood Pressure (Hypertension)?
Based on 16 studies with 810 participants, there is moderate evidence from clinical studies that Grape Seed Extract may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Grape Seed Extract should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 100-300 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Grape Seed Extract?
Reported side effects may include Generally well-tolerated, Mild headache (rare), Dizziness (rare), Nausea (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Grape Seed Extract and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 16 peer-reviewed studies with 810 total participants. The overall direction of effect is positive.

Related Evidence

Grape Seed Extract 用于其他健康状况

FDA 免责声明: 这些声明未经美国食品药品监督管理局(FDA)评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析,不构成医疗建议。在开始任何补充剂方案之前,请务必咨询您的医疗保健提供者。