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Grape Seed Extract ： High Blood Pressure (Hypertension)

B

Meta-analysis of 16 RCTs: systolic -6.08 mmHg. Greater effect in younger (<50) and obese participants. OPC standardization important for consistent results.

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            B

        

        

            
結論

            
            
Meta-analysis of 16 RCTs: systolic -6.08 mmHg. Greater effect in younger (<50) and obese participants. OPC standardization important for consistent results.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
16

        
研究数

    

    

        
810

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
グレード

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
100-300 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
150-300 mg/day standardized to 95% OPCs

                    

                    
                

                
                

                    上限量： Not formally established; up to 600 mg/day used in clinical trials
                

                
            

            

            

            
            

                推奨摂取タイミング： With or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild headache (rare)
                        
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  • 
                            ⚠
                            Dizziness (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea (rare)
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may increase bleeding risk)
                        
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  • 
                            ●
                            Blood pressure medications (additive hypotensive effect)
                        
    • 
                        
                        
  • 
                            ●
                            Iron supplements (tannins may reduce iron absorption)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Not formally established; up to 600 mg/day used in clinical trials
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Grape Seed Extract help with High Blood Pressure (Hypertension)?
            
        
        

            Based on 16 studies with 810 participants, there is moderate evidence from clinical studies that Grape Seed Extract may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Grape Seed Extract should I take for High Blood Pressure (Hypertension)?
            
        
        

            Studies have used various dosages. A commonly studied range is 100-300 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Grape Seed Extract?
            
        
        

            Reported side effects may include Generally well-tolerated, Mild headache (rare), Dizziness (rare), Nausea (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Grape Seed Extract and High Blood Pressure (Hypertension)?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 16 peer-reviewed studies with 810 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Grape Seed Extract 他の症状・状態について

                    

                        
                        
                            Endothelial Dysfunction
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。