Magnesium ： High Blood Pressure (Hypertension)

B エビデンス少なくとも1件のランダム化試験がこれを支持しており、おおむね一貫した結果が得られています。

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

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結論

Key Study Findings

Review

Dietary supplements and prevention of preeclampsia.

Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction 効果: ~50% risk reduction None

対象集団: Pregnant women with low calcium intake

Case Reports 13.0 weeks

A case report of Gitelman syndrome in children.

Dose: 3 g vs: None Outcome: pain reduction 効果: None None

対象集団: Hypokalemia

Review

Nutritional prevention of cognitive decline and dementia.

Dose: None vs: None Outcome: Cognitive decline prevention 効果: None None

対象集団: Older adults at risk of cognitive decline

Systematic Review

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on …

Dose: varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements vs: Placebo 効果: None None

Review

Prevention of hypokalemia caused by diuretics.

Dose: None vs: None Outcome: mineral status 効果: None None

対象集団: hypertensive patients

Randomized Controlled Trial n=48 26.0 weeks

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for …

Dose: 100 mg/d vs: control group Outcome: blood pressure 効果: None None

対象集団: hypertensive patients

Key Statistics

研究数

2028

参加者数

↑

Positive

グレード

Referenced Papers

Dietary supplements and prevention of preeclampsia. Review

Hypertension research : … 2025 10 件の引用

A case report of Gitelman syndrome in children. Case Report

Medicine 2023

Nutritional prevention of cognitive decline and dementia. Review

Acta bio-medica : … 2018 103 件の引用

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … Systematic Review

JBI database of … 2017 38 件の引用

Prevention of hypokalemia caused by diuretics. Review

Heart disease and … 1994

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … RCT

European journal of … 1986 22 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:: 310-420 mg/day
bloodpressuresupport:: 300-500 mg/day
cardiovascularsupport:: 300-400 mg/day elemental magnesium

上限量： 350 mg/day from supplements only (no UL for food magnesium)

研究で検討された用量

用量	期間	効果	N
500 mg daily	--	Positive	--
3 g	13.0 weeks	Mixed	--
None	--	Mixed	--
varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements	--	Mixed	--
None	--	Mixed	--
100 mg/d	26.0 weeks	Mixed	48

推奨摂取タイミング： With meals to reduce GI side effects; evening dosing may support sleep

Safety & Side Effects

報告されている副作用

⚠ Diarrhea (especially magnesium oxide and citrate)
⚠ Nausea
⚠ Abdominal cramping
⚠ Excessive doses may cause hypotension or cardiac depression

既知の相互作用

● Bisphosphonates (reduced absorption — separate by 2 hours)
● Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
● Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
● Proton pump inhibitors (long-term use may cause hypomagnesemia)

耐容上限摂取量： 350 mg/day from supplements only (no UL for food magnesium)

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does Magnesium help with High Blood Pressure (Hypertension)?

Based on 34 studies with 2,028 participants, there is moderate evidence from clinical studies that Magnesium may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).

How much Magnesium should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Magnesium?

Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Magnesium and High Blood Pressure (Hypertension)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 34 peer-reviewed studies with 2,028 total participants. The overall direction of effect is positive.

に関する他の成分： High Blood Pressure (Hypertension)

Beetroot Extract A Garlic A Potassium B Quercetin B Grape Seed Extract B Coenzyme Q10 (CoQ10) B

Magnesium 他の症状・状態について

Cardiac Arrhythmia B Coronary Artery Disease (CAD) C

総合評価

Evidence Strength72%

High confidence

研究の内訳

RCT (1)Meta (0)Other (33)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る： High Blood Pressure (Hypertension)

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References

[1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
[2] Jing Ying et al.. Medicine (Baltimore). 2023. A case report of Gitelman syndrome in children. doi:10.1097/MD.0000000000033509 PubMed
[3] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed
[4] Delia McCabe et al.. JBI Database System Rev Implement Rep. 2017. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … doi:10.11124/JBISRIR-2016-002965 PubMed
[5] E Bourke et al.. Heart Dis Stroke. 1994. Prevention of hypokalemia caused by diuretics. PubMed
[6] T Dyckner et al.. Eur J Clin Pharmacol. 1986. Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … doi:10.1007/BF00542411 PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Magnesium ： High Blood Pressure (Hypertension)

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結論

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

一般的な使用量

研究で検討された用量

Safety & Side Effects

報告されている副作用

既知の相互作用

Frequently Asked Questions

Related Evidence

に関する他の成分： High Blood Pressure (Hypertension)

Magnesium 他の症状・状態について

References