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Magnesium ： Coronary Artery Disease (CAD)

C

Prospective cohorts show 22% lower CHD risk with higher magnesium intake. Interventional data is limited. Mechanistic rationale is strong (anti-inflammatory, anti-arrhythmic effects).

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            C

        

        

            
結論

            
            
Prospective cohorts show 22% lower CHD risk with higher magnesium intake. Interventional data is limited. Mechanistic rationale is strong (anti-inflammatory, anti-arrhythmic effects).

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
5

        
研究数

    

    

        
350

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
グレード

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
general:

                        
310-420 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
300-500 mg/day

                    

                    
                    

                        
cardiovascularsupport:

                        
300-400 mg/day elemental magnesium

                    

                    
                

                
                

                    上限量： 350 mg/day from supplements only (no UL for food magnesium)
                

                
            

            

            

            
            

                推奨摂取タイミング： With meals to reduce GI side effects; evening dosing may support sleep
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Diarrhea (especially magnesium oxide and citrate)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea
                        
    • 
                        
                        
  • 
                            ⚠
                            Abdominal cramping
                        
    • 
                        
                        
  • 
                            ⚠
                            Excessive doses may cause hypotension or cardiac depression
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Bisphosphonates (reduced absorption — separate by 2 hours)
                        
    • 
                        
                        
  • 
                            ●
                            Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
                        
    • 
                        
                        
  • 
                            ●
                            Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
                        
    • 
                        
                        
  • 
                            ●
                            Proton pump inhibitors (long-term use may cause hypomagnesemia)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： 350 mg/day from supplements only (no UL for food magnesium)
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Magnesium help with Coronary Artery Disease (CAD)?
            
        
        

            Based on 5 studies with 350 participants, there is limited but promising evidence that Magnesium may support Coronary Artery Disease (CAD) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Magnesium should I take for Coronary Artery Disease (CAD)?
            
        
        

            Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Magnesium?
            
        
        

            Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Magnesium and Coronary Artery Disease (CAD)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 5 peer-reviewed studies with 350 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
に関する他の成分： Coronary Artery Disease (CAD)

                    

                        
                        
                            Omega-3 Fatty Acids (EPA/DHA)
                            B

                        
                        
                        
                            Folate (Vitamin B9)
                            C

                        
                        
                        
                            Selenium
                            C

                        
                        
                    

                

                

                
                

                    
Magnesium 他の症状・状態について

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            B

                        
                        
                        
                            Cardiac Arrhythmia
                            B

                        
                        
                    

                

                
            

        

        

    


    
    












    

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