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Grape Seed Extract
Grape Seed Extract

antioxidant

别名: OPC, Oligomeric Proanthocyanidins, Proanthocyanidin, Vitis vinifera Extract

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About





            

                
Grape seed extract is a rich source of oligomeric proanthocyanidins (OPCs) with antioxidant capacity 20-50x greater than vitamins C and E. A 2016 meta-analysis of 16 RCTs (810 participants) found it significantly reduced systolic blood pressure by 6.08 mmHg, with greater effects in younger and obese participants.

            

        

        

        
        
        

            

  
How It Works





            

                
Rich source of oligomeric proanthocyanidins (OPCs) that inhibit LDL oxidation with potency exceeding vitamins C and E; enhances endothelial nitric oxide production; inhibits ACE in a manner similar to pharmaceutical ACE inhibitors; reduces platelet aggregation; strengthens capillary walls.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                健康状况
                                等级
                                研究数量
                                受试者
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Blood Pressure (Hypertension)
                                    
                                
                                
                                    B

                                
                                
                                    16
                                
                                
                                    810
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                            

                                
                                    
                                        Endothelial Dysfunction
                                    
                                
                                
                                    C

                                
                                
                                    6
                                
                                
                                    350
                                
                                
                                    
                                        查看 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Generally well-tolerated
                
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                    Mild headache (rare)
                
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                    Dizziness (rare)
                
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                    Nausea (rare)
                
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Drug & Supplement Interactions





            
    
                
                
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                    Anticoagulants (may increase bleeding risk)
                
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                    Blood pressure medications (additive hypotensive effect)
                
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                    Iron supplements (tannins may reduce iron absorption)
                
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                请务必告知您的医疗保健提供者您正在服用的所有补充剂。
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Resveratrol
                    
                
                
                
                    Astaxanthin
                    
                
                
                
                    Quercetin
                    
                
                
                
                    Lycopene
                    
                
                
            

        

        
    


    
    












    

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