LycopeneLycopene
antioxidant
别名: Tomato Extract, Lyc-O-Mato, All-trans-Lycopene
About
Lycopene is the most efficient singlet oxygen quencher among dietary carotenoids and accumulates in LDL particles where it inhibits oxidation. A 2017 meta-analysis of 6 RCTs found lycopene at 12-75 mg/day significantly reduced systolic blood pressure by 5.6 mmHg. Cooking tomatoes with fat increases lycopene bioavailability 2-3 fold.
How It Works
The most efficient singlet oxygen quencher among dietary carotenoids; accumulates in LDL particles where it inhibits oxidation more effectively than beta-carotene; reduces endothelial activation and monocyte adhesion; inhibits HMG-CoA reductase activity (statin-like mechanism) reducing cholesterol synthesis.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| High Blood Pressure (Hypertension) | B | 6 | 400 | 查看 → |
| Atherosclerosis | D | 3 | 200 | 查看 → |
Side Effects
- Generally well-tolerated
- Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible
Drug & Supplement Interactions
- Blood pressure medications (may have mild additive effect)
- Beta-carotene (may compete for absorption)
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Related Ingredients
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