Vitamin E 관련 동맥경화증

C 근거 소규모 연구에서의 근거는 제한적이지만, 일부 긍정적인 신호가 존재합니다.

Strong mechanistic rationale (LDL oxidation inhibition) but large RCTs (HOPE, GISSI-Prevenzione) show no benefit. Meta-analysis suggests potential harm at >=400 IU/day. AHA does not recommend supplementation.

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결론

Key Study Findings

Review

Navigating the Effects of Anti-Atherosclerotic Supplements and Acknowledging Associated Bleeding Risks.

Dose: None vs: None Outcome: None 효과: None None

대상 집단: Review of anti-atherosclerotic supplements and bleeding

Other

Extensive Bioactivity of Astaxanthin from Haematococcus pluvialis in Human.

Dose: None vs: None Outcome: None 효과: None None

대상 집단: None

Other

Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults …

Dose: None vs: Conventional treatment Outcome: effect of a dietary supplement on chronic inflammation … 효과: None p < 0.05

대상 집단: None

Review

Nutrient intake, nutritional status, and cognitive function with aging.

Dose: None vs: None Outcome: None 효과: None None

대상 집단: Aging adults (nutrition and cognition)

Review

Role of reactive oxygen species and antioxidants in atopic dermatitis.

Dose: None vs: None Outcome: Role of oxidative stress in atopic dermatitis 효과: None None

대상 집단: Patients with atopic dermatitis

Review

Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease.

Dose: None vs: None Outcome: Astaxanthin: a novel potential treatment for oxidative stress … 효과: None None

대상 집단: None

Key Statistics

연구

50000

참여자

↔

Mixed

등급

Referenced Papers

Navigating the Effects of Anti-Atherosclerotic Supplements and Acknowledging Associated Bleeding Risks. Review

International journal of … 2025 1 인용

Extensive Bioactivity of Astaxanthin from Haematococcus pluvialis in Human. Other

Advances in experimental … 2021 13 인용

Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. Other

Nutrients 2020 16 인용

Nutrient intake, nutritional status, and cognitive function with aging. Review

Annals of the … 2016 89 인용

Role of reactive oxygen species and antioxidants in atopic dermatitis. Other

Journal of clinical … 2013 178 인용

Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease. Review

The American journal … 2008 441 인용

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

note:: High-dose supplementation no longer recommended based on clinical trial evidence
general:: 15 mg/day (22.4 IU)

상한량: 1,000 mg/day (1,500 IU natural, 1,100 IU synthetic)

연구에서 사용된 용량

용량	기간	효과	N
None	--	Mixed	--
None	--	Positive	--
None	--	Mixed	--
None	--	Mixed	--
None	--	Positive	--
None	--	Positive	--

권장 복용 시간: With meals containing fat

Safety & Side Effects

보고된 부작용

⚠ Increased bleeding risk at high doses
⚠ Possible increased all-cause mortality at >=400 IU/day
⚠ Increased heart failure hospitalization risk (HOPE/HOPE-TOO)
⚠ Nausea, diarrhea, fatigue at high doses

알려진 상호작용

● Anticoagulants (increased bleeding risk)
● Statins and niacin (may blunt HDL-raising effect)
● Chemotherapy and radiation (theoretical interference with oxidative mechanisms)
● Vitamin K (may antagonize at high doses)

일일 최대 섭취 허용량: 1,000 mg/day (1,500 IU natural, 1,100 IU synthetic)

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does Vitamin E help with 동맥경화증?

Based on 15 studies with 50,000 participants, there is limited but promising evidence that Vitamin E may support 동맥경화증 management. Our evidence grade is C (Some Evidence).

How much Vitamin E should I take for 동맥경화증?

Studies have used various dosages. A commonly studied range is High-dose supplementation no longer recommended based on clinical trial evidence. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Vitamin E?

Reported side effects may include Increased bleeding risk at high doses, Possible increased all-cause mortality at >=400 IU/day, Increased heart failure hospitalization risk (HOPE/HOPE-TOO), Nausea, diarrhea, fatigue at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Vitamin E and 동맥경화증?

We rate the evidence as Grade C (Some Evidence). This rating is based on 15 peer-reviewed studies with 50,000 total participants. The overall direction of effect is mixed.

한눈에 보기

Evidence Strength52%

Moderate confidence

연구 분석

RCT (0)Meta (0)Other (15)

대안 비교

이 건강 상태에 대한 다른 성분의 비교 결과를 확인하세요.

모든 성분 보기: 동맥경화증

자세히 알아보기

References

[1] Maria-Zinaida Dobre et al.. Int J Mol Sci. 2025. Navigating the Effects of Anti-Atherosclerotic Supplements and Acknowledging Associated Bleeding Risks. doi:10.3390/ijms262010183 PubMed
[2] Eiji Yamashita. Adv Exp Med Biol. 2021. Extensive Bioactivity of Astaxanthin from Haematococcus pluvialis in Human. doi:10.1007/978-981-15-7360-6_23 PubMed
[3] Raúl Francisco Pastor et al.. Nutrients. 2020. Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. doi:10.3390/nu12103149 PubMed
[4] Katherine L Tucker. Ann N Y Acad Sci. 2016. Nutrient intake, nutritional status, and cognitive function with aging. doi:10.1111/nyas.13062 PubMed
[5] N Sivaranjani et al.. J Clin Diagn Res. 2013. Role of reactive oxygen species and antioxidants in atopic dermatitis. doi:10.7860/JCDR/2013/6635.3732 PubMed
[6] Fredric J Pashkow et al.. Am J Cardiol. 2008. Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease. doi:10.1016/j.amjcard.2008.02.010 PubMed

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.

Vitamin E 관련 동맥경화증

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결론

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

일반적으로 사용되는 용량

연구에서 사용된 용량

Safety & Side Effects

보고된 부작용

알려진 상호작용

Frequently Asked Questions

Related Evidence

관련 다른 성분: 동맥경화증

References