Peripheral Artery Disease (PAD)
Prevalence: 8.5 million US adults; 12-20% of adults >60 years
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About
Atherosclerotic narrowing of arteries supplying the extremities, primarily legs. Ankle-brachial index (ABI) <0.9 is diagnostic. PAD is a marker for systemic atherosclerosis and is associated with 2-3x increased risk of MI and stroke.
Common Symptoms
Intermittent claudication (leg pain with walking)
Numbness/weakness in legs
Cold legs/feet
Non-healing wounds
Reduced pulse
Risk Factors
- Smoking (strongest risk factor)
- Diabetes
- Hypertension
- Dyslipidemia
- Age >50
- Chronic kidney disease
Frequently Asked Questions
How is the evidence for Peripheral Artery Disease (PAD) supplements graded?
We grade supplements on an A-F scale based on clinical study quality, consistency of results, sample sizes, and study design. Grade A indicates strong evidence from multiple clinical trials, while Grade D indicates preliminary evidence requiring further research.
What are common symptoms of Peripheral Artery Disease (PAD)?
Common symptoms associated with Peripheral Artery Disease (PAD) include Intermittent claudication (leg pain with walking), Numbness/weakness in legs, Cold legs/feet, Non-healing wounds, Reduced pulse. If you are experiencing these symptoms, consult a healthcare professional for proper diagnosis and treatment options.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.