Lycopene 관련 동맥경화증
D 연구 예비 연구(실험실 연구, 증례 보고)만 존재합니다.EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.
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D
결론
EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.
Key Study Findings
Other
Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine …
Dose: 50 mg/kg lycopene in mice
vs: HFD control mice
Outcome: Cognitive function (Y-maze, MWM, novel object recognition)
효과: None
None
대상 집단: HFD-induced obese male C57BL/6 mice
Review
Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: review of plant-derived anti-inflammatory compounds for chronic disease prevention
Observational Study
n=60
Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive …
Dose: None
vs: None
Outcome: Carotenoid moderation of cfPWV-cognition relationship
효과: Beta=0.53, p=0.04 for lutein moderation
0.02
대상 집단: Adults, mean age 38.6, 70% female
Meta-Analysis
Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.
Dose: None
vs: Placebo
Outcome: Blood pressure
효과: None
None
대상 집단: None
systematic review
n=90
A systematic review on the impact of nutrition and possible supplementation on the deficiency of …
Dose: None
vs: Placebo
효과: None
None
Randomized Controlled Trial
Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease.
Dose: None
vs: None
Outcome: Cognitive decline
효과: None
None
대상 집단: Alzheimer's disease patients
Key Statistics
3
연구
200
참여자
↑
Positive
D
등급
Referenced Papers
International journal of …
2025
32 인용
Clinical nutrition (Edinburgh, …
2025
1 인용
The Journal of …
2025
A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, …
Systematic Review
Archives of gynecology …
2024
18 인용
International journal of …
2024
11 인용
Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.
Meta-Analysis
Nutrients
2024
6 인용
Journal of sleep …
2014
236 인용
Current atherosclerosis reports
2009
122 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 6-15 mg/day
- cardiovascularsupport:
- 15-30 mg/day
상한량: Not formally established; up to 75 mg/day used in clinical trials
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| 50 mg/kg lycopene in mice | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 60 |
| None | -- | Neutral | -- |
| None | -- | Negative | 90 |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
권장 복용 시간: With meals containing fat (cooking with olive oil enhances absorption 2-3x)
Safety & Side Effects
보고된 부작용
- ⚠ Generally well-tolerated
- ⚠ Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible
알려진 상호작용
- ● Blood pressure medications (may have mild additive effect)
- ● Beta-carotene (may compete for absorption)
일일 최대 섭취 허용량: Not formally established; up to 75 mg/day used in clinical trials
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Lycopene help with 동맥경화증?
Based on 3 studies with 200 participants, there is preliminary evidence that needs more research that Lycopene may support 동맥경화증 management. Our evidence grade is D (Very Early Research).
How much Lycopene should I take for 동맥경화증?
Studies have used various dosages. A commonly studied range is 6-15 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Lycopene?
Reported side effects may include Generally well-tolerated, Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Lycopene and 동맥경화증?
We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 동맥경화증
Lycopene 다른 건강 상태에 대한 근거
References
- [1] Kazuhiko Nakadate et al.. Int J Mol Sci. 2025. Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. doi:10.3390/ijms26115206 PubMed
- [2] Yuqing Wu et al.. Clin Nutr. 2025. Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. doi:10.1016/j.clnu.2025.06.005 PubMed
- [3] Shreya Verma et al.. J Nutr. 2025. Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function. doi:10.1016/j.tjnut.2025.08.029 PubMed
- [4] Friederike Wylenzek et al.. Arch Gynecol Obstet. 2024. A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … doi:10.1007/s00404-024-07555-6 PubMed
- [5] Jolanta Flieger et al.. Int J Mol Sci. 2024. Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease. doi:10.3390/ijms25168982 PubMed
- [6] Sitong Wan et al.. Nutrients. 2024. Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. doi:10.3390/nu16142213 PubMed
- [7] Michael A Grandner et al.. J Sleep Res. 2014. Sleep symptoms associated with intake of specific dietary nutrients. doi:10.1111/jsr.12084 PubMed
- [8] Graziano Riccioni. Curr Atheroscler Rep. 2009. Carotenoids and cardiovascular disease. doi:10.1007/s11883-009-0065-z PubMed
FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.