Lycopene cho Atherosclerosis

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EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

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Kết luận

EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

Key Study Findings

Other

Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine …

Dose: 50 mg/kg lycopene in mice so với: HFD control mice Outcome: Cognitive function (Y-maze, MWM, novel object recognition) Hiệu quả: None None

Đối tượng nghiên cứu: HFD-induced obese male C57BL/6 mice

Review

Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications.

Dose: None so với: None Outcome: None Hiệu quả: None None

Đối tượng nghiên cứu: review of plant-derived anti-inflammatory compounds for chronic disease prevention

Observational Study n=60

Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive …

Dose: None so với: None Outcome: Carotenoid moderation of cfPWV-cognition relationship Hiệu quả: Beta=0.53, p=0.04 for lutein moderation 0.02

Đối tượng nghiên cứu: Adults, mean age 38.6, 70% female

Meta-Analysis

Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.

Dose: None so với: Placebo Outcome: Blood pressure Hiệu quả: None None

Đối tượng nghiên cứu: None

systematic review n=90

A systematic review on the impact of nutrition and possible supplementation on the deficiency of …

Dose: None so với: Placebo Hiệu quả: None None

Randomized Controlled Trial

Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease.

Dose: None so với: None Outcome: Cognitive decline Hiệu quả: None None

Đối tượng nghiên cứu: Alzheimer's disease patients

Key Statistics

Nghiên cứu

200

Người tham gia

↑

Positive

Xếp hạng

Referenced Papers

Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. Review

International journal of … 2025 32 trích dẫn

Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. Other

Clinical nutrition (Edinburgh, … 2025 1 trích dẫn

Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function. Other

The Journal of … 2025

A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … Systematic Review

Archives of gynecology … 2024 18 trích dẫn

Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease. Review

International journal of … 2024 11 trích dẫn

Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. Meta-Analysis

Nutrients 2024 6 trích dẫn

Sleep symptoms associated with intake of specific dietary nutrients. Other

Journal of sleep … 2014 236 trích dẫn

Carotenoids and cardiovascular disease. Review

Current atherosclerosis reports 2009 122 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:: 6-15 mg/day
cardiovascularsupport:: 15-30 mg/day

Giới hạn trên: Not formally established; up to 75 mg/day used in clinical trials

Liều lượng đã nghiên cứu

Liều lượng	Thời gian	Hiệu quả	N
50 mg/kg lycopene in mice	--	Positive	--
None	--	Positive	--
None	--	Positive	60
None	--	Neutral	--
None	--	Negative	90
None	--	Positive	--
None	--	Mixed	--

Thời điểm dùng tốt nhất: With meals containing fat (cooking with olive oil enhances absorption 2-3x)

Safety & Side Effects

Tác dụng phụ đã được báo cáo

⚠ Generally well-tolerated
⚠ Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible

Tương tác đã biết

● Blood pressure medications (may have mild additive effect)
● Beta-carotene (may compete for absorption)

Mức hấp thụ tối đa cho phép: Not formally established; up to 75 mg/day used in clinical trials

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Lycopene help with Atherosclerosis?

Based on 3 studies with 200 participants, there is preliminary evidence that needs more research that Lycopene may support Atherosclerosis management. Our evidence grade is D (Very Early Research).

How much Lycopene should I take for Atherosclerosis?

Studies have used various dosages. A commonly studied range is 6-15 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Lycopene?

Reported side effects may include Generally well-tolerated, Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Lycopene and Atherosclerosis?

We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.

Các thành phần khác cho Atherosclerosis

Nattokinase B Vitamin E C Resveratrol C Quercetin D Flaxseed Oil D Olive Leaf Extract D

Lycopene cho các tình trạng khác

High Blood Pressure (Hypertension) B

Đánh giá nhanh

EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

Evidence Strength30%

Low confidence

Phân tích nghiên cứu

RCT (0)Meta (1)Other (2)

So sánh lựa chọn thay thế

Xem các thành phần khác so sánh như thế nào cho tình trạng này.

Xem tất cả thành phần cho Atherosclerosis

Tìm hiểu thêm

References

[1] Kazuhiko Nakadate et al.. Int J Mol Sci. 2025. Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. doi:10.3390/ijms26115206 PubMed
[2] Yuqing Wu et al.. Clin Nutr. 2025. Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. doi:10.1016/j.clnu.2025.06.005 PubMed
[3] Shreya Verma et al.. J Nutr. 2025. Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function. doi:10.1016/j.tjnut.2025.08.029 PubMed
[4] Friederike Wylenzek et al.. Arch Gynecol Obstet. 2024. A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … doi:10.1007/s00404-024-07555-6 PubMed
[5] Jolanta Flieger et al.. Int J Mol Sci. 2024. Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease. doi:10.3390/ijms25168982 PubMed
[6] Sitong Wan et al.. Nutrients. 2024. Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. doi:10.3390/nu16142213 PubMed
[7] Michael A Grandner et al.. J Sleep Res. 2014. Sleep symptoms associated with intake of specific dietary nutrients. doi:10.1111/jsr.12084 PubMed
[8] Graziano Riccioni. Curr Atheroscler Rep. 2009. Carotenoids and cardiovascular disease. doi:10.1007/s11883-009-0065-z PubMed

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Lycopene cho Atherosclerosis

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Kết luận

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Liều lượng thường dùng

Liều lượng đã nghiên cứu

Safety & Side Effects

Tác dụng phụ đã được báo cáo

Tương tác đã biết

Frequently Asked Questions

Related Evidence

Các thành phần khác cho Atherosclerosis

Lycopene cho các tình trạng khác

References