Lycopene pour Atherosclerosis

D Recherche Seules des recherches préliminaires existent (études en laboratoire, rapports de cas).

EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

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En conclusion

EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

Key Study Findings

Other

Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine …

Dose: 50 mg/kg lycopene in mice vs: HFD control mice Outcome: Cognitive function (Y-maze, MWM, novel object recognition) Effet: None None

Population: HFD-induced obese male C57BL/6 mice

Review

Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications.

Dose: None vs: None Outcome: None Effet: None None

Population: review of plant-derived anti-inflammatory compounds for chronic disease prevention

Observational Study n=60

Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive …

Dose: None vs: None Outcome: Carotenoid moderation of cfPWV-cognition relationship Effet: Beta=0.53, p=0.04 for lutein moderation 0.02

Population: Adults, mean age 38.6, 70% female

Meta-Analysis

Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.

Dose: None vs: Placebo Outcome: Blood pressure Effet: None None

Population: None

systematic review n=90

A systematic review on the impact of nutrition and possible supplementation on the deficiency of …

Dose: None vs: Placebo Effet: None None

Randomized Controlled Trial

Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease.

Dose: None vs: None Outcome: Cognitive decline Effet: None None

Population: Alzheimer's disease patients

Key Statistics

Études

200

Participants

↑

Positive

Note

Referenced Papers

Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. Review

International journal of … 2025 32 citations

Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. Other

Clinical nutrition (Edinburgh, … 2025 1 citations

Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function. Other

The Journal of … 2025

A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … Systematic Review

Archives of gynecology … 2024 18 citations

Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease. Review

International journal of … 2024 11 citations

Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. Meta-Analysis

Nutrients 2024 6 citations

Sleep symptoms associated with intake of specific dietary nutrients. Other

Journal of sleep … 2014 236 citations

Carotenoids and cardiovascular disease. Review

Current atherosclerosis reports 2009 122 citations

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

general:: 6-15 mg/day
cardiovascularsupport:: 15-30 mg/day

Limite supérieure : Not formally established; up to 75 mg/day used in clinical trials

Posologies étudiées dans la recherche

Posologie	Durée	Effet	N
50 mg/kg lycopene in mice	--	Positive	--
None	--	Positive	--
None	--	Positive	60
None	--	Neutral	--
None	--	Negative	90
None	--	Positive	--
None	--	Mixed	--

Moment optimal de prise : With meals containing fat (cooking with olive oil enhances absorption 2-3x)

Safety & Side Effects

Effets indésirables signalés

⚠ Generally well-tolerated
⚠ Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible

Interactions connues

● Blood pressure medications (may have mild additive effect)
● Beta-carotene (may compete for absorption)

Apport maximal tolérable : Not formally established; up to 75 mg/day used in clinical trials

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Lycopene help with Atherosclerosis?

Based on 3 studies with 200 participants, there is preliminary evidence that needs more research that Lycopene may support Atherosclerosis management. Our evidence grade is D (Very Early Research).

How much Lycopene should I take for Atherosclerosis?

Studies have used various dosages. A commonly studied range is 6-15 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Lycopene?

Reported side effects may include Generally well-tolerated, Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Lycopene and Atherosclerosis?

We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 200 total participants. The overall direction of effect is positive.

Autres ingrédients pour Atherosclerosis

Nattokinase B Vitamin E C Resveratrol C Quercetin D Flaxseed Oil D Olive Leaf Extract D

Lycopene pour d'autres pathologies

High Blood Pressure (Hypertension) B

Verdict rapide

EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.

Evidence Strength30%

Low confidence

Synthèse des études

RCT (0)Meta (1)Other (2)

Comparer les alternatives

Découvrez comment d'autres ingrédients se comparent pour cette condition.Découvrez comment d'autres ingrédients se comparent pour cette pathologie.

Voir tous les ingrédients pour Atherosclerosis

En savoir plus

References

[1] Kazuhiko Nakadate et al.. Int J Mol Sci. 2025. Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. doi:10.3390/ijms26115206 PubMed
[2] Yuqing Wu et al.. Clin Nutr. 2025. Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. doi:10.1016/j.clnu.2025.06.005 PubMed
[3] Shreya Verma et al.. J Nutr. 2025. Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function. doi:10.1016/j.tjnut.2025.08.029 PubMed
[4] Friederike Wylenzek et al.. Arch Gynecol Obstet. 2024. A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … doi:10.1007/s00404-024-07555-6 PubMed
[5] Jolanta Flieger et al.. Int J Mol Sci. 2024. Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease. doi:10.3390/ijms25168982 PubMed
[6] Sitong Wan et al.. Nutrients. 2024. Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. doi:10.3390/nu16142213 PubMed
[7] Michael A Grandner et al.. J Sleep Res. 2014. Sleep symptoms associated with intake of specific dietary nutrients. doi:10.1111/jsr.12084 PubMed
[8] Graziano Riccioni. Curr Atheroscler Rep. 2009. Carotenoids and cardiovascular disease. doi:10.1007/s11883-009-0065-z PubMed

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.

Lycopene pour Atherosclerosis

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En conclusion

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Posologies couramment utilisées

Posologies étudiées dans la recherche

Safety & Side Effects

Effets indésirables signalés

Interactions connues

Frequently Asked Questions

Related Evidence

Autres ingrédients pour Atherosclerosis

Lycopene pour d'autres pathologies

References