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Olive Leaf Extract pour Atherosclerosis

D Recherche Seules des recherches préliminaires existent (études en laboratoire, rapports de cas).

Oleuropein may help reduce ox-LDL (a key atherogenic particle). PREDIMED trial supports cardiovascular benefit of olive polyphenols, but used oil rather than leaf extract specifically.

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            D

        

        

            
En conclusion

            
            
Oleuropein may help reduce ox-LDL (a key atherogenic particle). PREDIMED trial supports cardiovascular benefit of olive polyphenols, but used oil rather than leaf extract specifically.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Randomized Controlled Trial
                
                
                
                8 weeks
                
                
                Double-blind
                
            

            
                Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers …
            
            

                
                Dose: 180 mg/d
                
                
                vs: None
                
                
                Outcome: lipid levels
                
                
                Effet: None
                
                
                p < 0.001
                
            

            
            
Population: Patients with dyslipidemia

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
Études

    

    

        
100

        
Participants

    

    

        
            
            ↑
            
        
        
Positive

    

    

        D

        
Note

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with …
                        
                        
                            
                                RCT
                            
                            
                            
                        
                    

                    

                        Nutrients
                        2023
                        
                        8 citations
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Posologies couramment utilisées

                

                    
                    

                        
general:

                        
500 mg BID

                    

                    
                    

                        
oleuropeincontent:

                        
15-20% standardization

                    

                    
                    

                        
standardizedextract:

                        
500-1,000 mg/day (EFLA 943)

                    

                    
                

                
                

                    Limite supérieure : Not formally established; well-tolerated up to 1,000 mg/day in clinical trials
                

                
            

            

            
            

                
Posologies étudiées dans la recherche

                

                    

                        
                            

                                Posologie
                                Durée
                                Effet
                                N
                            

                        
                        
                            
                            

                                180 mg/d
                                8 weeks
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Moment optimal de prise : With meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effets indésirables signalés

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Dizziness (if blood pressure drops significantly)
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache (rare)
                        
    • 
                        
                    

                

                

                
                

                    
Interactions connues

                    
    
                        
                        
  • 
                            ●
                            Antihypertensives (additive blood pressure lowering — monitor BP)
                        
    • 
                        
                        
  • 
                            ●
                            Diabetes medications (may lower blood sugar)
                        
    • 
                        
                        
  • 
                            ●
                            Anticoagulants (mild theoretical interaction)
                        
    • 
                        
                    

                

                

                
                

                    

                        Apport maximal tolérable : Not formally established; well-tolerated up to 1,000 mg/day in clinical trials
                    

                

                
            

            

                Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Olive Leaf Extract help with Atherosclerosis?
            
        
        

            Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Olive Leaf Extract may support Atherosclerosis management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Olive Leaf Extract should I take for Atherosclerosis?
            
        
        

            Studies have used various dosages. A commonly studied range is 500 mg BID. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Olive Leaf Extract?
            
        
        

            Reported side effects may include Generally well-tolerated, Mild gastrointestinal discomfort, Dizziness (if blood pressure drops significantly), Headache (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Olive Leaf Extract and Atherosclerosis?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Olive Leaf Extract pour d'autres pathologies

                    

                        
                        
                            High Blood Pressure (Hypertension)
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Nicholas Angelopoulos et al..
      Nutrients.
      2023.
      Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with …
      doi:10.3390/nu15122682
      PubMed
    
    2. 
    
  















    

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