Lycopene para Atherosclerosis
D Pesquisa Existem apenas investigaciones preliminares (estudos laboratoriais, relatórios de casos).EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.
Conclusão
EURAMIC study showed association between adipose lycopene and lower MI risk. Cambridge study improved FMD in CAD patients. Interventional evidence is limited.
Key Study Findings
População: HFD-induced obese male C57BL/6 mice
Key Statistics
3
Estudos
200
Participantes
Positive
Nota
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Dosagens Comumente Utilizadas
- general:
- 6-15 mg/day
- cardiovascularsupport:
- 15-30 mg/day
Limite superior: Not formally established; up to 75 mg/day used in clinical trials
Dosagens Estudadas em Pesquisas
| Dosagem | Duração | Efeito | N |
|---|---|---|---|
| 50 mg/kg lycopene in mice | -- | Positive | -- |
Melhor horário: With meals containing fat (cooking with olive oil enhances absorption 2-3x)
Safety & Side Effects
Efeitos Colaterais Relatados
- ⚠ Generally well-tolerated
- ⚠ Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible
Interações Conhecidas
- ● Blood pressure medications (may have mild additive effect)
- ● Beta-carotene (may compete for absorption)
Ingestão máxima tolerável: Not formally established; up to 75 mg/day used in clinical trials
Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.
Frequently Asked Questions
Does Lycopene help with Atherosclerosis?
How much Lycopene should I take for Atherosclerosis?
Are there side effects of Lycopene?
How strong is the evidence for Lycopene and Atherosclerosis?
Related Evidence
Outros ingredientes para Atherosclerosis
Lycopene para outras condições
References
- [1] Kazuhiko Nakadate et al.. Int J Mol Sci. 2025. Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. doi:10.3390/ijms26115206 PubMed
- [2] Yuqing Wu et al.. Clin Nutr. 2025. Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway. doi:10.1016/j.clnu.2025.06.005 PubMed
- [3] Shreya Verma et al.. J Nutr. 2025. Vascular Roads to a Healthier Brain: Lutein Moderates the Influence of Arterial Stiffness on Cognitive Function. doi:10.1016/j.tjnut.2025.08.029 PubMed
- [4] Friederike Wylenzek et al.. Arch Gynecol Obstet. 2024. A systematic review on the impact of nutrition and possible supplementation on the deficiency of vitamin complexes, iron, omega-3-fatty acids, … doi:10.1007/s00404-024-07555-6 PubMed
- [5] Jolanta Flieger et al.. Int J Mol Sci. 2024. Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease. doi:10.3390/ijms25168982 PubMed
- [6] Sitong Wan et al.. Nutrients. 2024. Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. doi:10.3390/nu16142213 PubMed
- [7] Michael A Grandner et al.. J Sleep Res. 2014. Sleep symptoms associated with intake of specific dietary nutrients. doi:10.1111/jsr.12084 PubMed
- [8] Graziano Riccioni. Curr Atheroscler Rep. 2009. Carotenoids and cardiovascular disease. doi:10.1007/s11883-009-0065-z PubMed
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.