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Lycopene para High Blood Pressure (Hypertension)

B Evidências Pelo menos um ensaio aleatorizado apoia esta conclusão, com resultados maioritariamente consistentes.

Meta-analysis of 6 RCTs: systolic -5.6 mmHg. Improved endothelial function. Cooking with oil enhances absorption 2-3x. Strong observational associations with lower MI risk.

B

Conclusão

Meta-analysis of 6 RCTs: systolic -5.6 mmHg. Improved endothelial function. Cooking with oil enhances absorption 2-3x. Strong observational associations with lower MI risk.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction Efeito: ~50% risk reduction

População: Pregnant women with low calcium intake

Key Statistics

6

Estudos

400

Participantes

↑

Positive

B

Nota

Referenced Papers

Dietary supplements and prevention of preeclampsia. Review
Hypertension research : … 2025 10 citações
Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled … RCT
The American journal … 2025 2 citações
Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. Meta-Analysis
Nutrients 2024 6 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

general:
6-15 mg/day
cardiovascularsupport:
15-30 mg/day

Limite superior: Not formally established; up to 75 mg/day used in clinical trials

Dosagens Estudadas em Pesquisas

Dosagem Duração Efeito N
500 mg daily -- Positive --

Melhor horário: With meals containing fat (cooking with olive oil enhances absorption 2-3x)

Safety & Side Effects

Efeitos Colaterais Relatados

  • ⚠ Generally well-tolerated
  • ⚠ Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible

Interações Conhecidas

  • ● Blood pressure medications (may have mild additive effect)
  • ● Beta-carotene (may compete for absorption)

Ingestão máxima tolerável: Not formally established; up to 75 mg/day used in clinical trials

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Lycopene help with High Blood Pressure (Hypertension)?
Based on 6 studies with 400 participants, there is moderate evidence from clinical studies that Lycopene may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Lycopene should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 6-15 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Lycopene?
Reported side effects may include Generally well-tolerated, Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Lycopene and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Lycopene para outras condições

Atherosclerosis D

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References

  
    
    
    
  1. 
      [1]
      Takafumi Ushida et al..
      Hypertens Res.
      2025.
      Dietary supplements and prevention of preeclampsia.
      doi:10.1038/s41440-025-02144-9
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Xiaoran Liu et al..
      Am J Clin Nutr.
      2025.
      Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled …
      doi:10.1016/j.ajcnut.2025.08.012
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Sitong Wan et al..
      Nutrients.
      2024.
      Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis.
      doi:10.3390/nu16142213
      PubMed
    
    4. 
    
  















    

        Aviso Legal da FDA:
        Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.