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L-Citrulline para High Blood Pressure (Hypertension)

C Evidências Evidência limitada de estudos de pequena dimensão, mas existem alguns sinais positivos.

Systolic -4.1 mmHg in meta-analysis. May have superior pharmacokinetics vs. arginine for sustained nitric oxide production. Growing evidence base but still smaller than other BP-lowering supplements.

C

Conclusão

Systolic -4.1 mmHg in meta-analysis. May have superior pharmacokinetics vs. arginine for sustained nitric oxide production. Growing evidence base but still smaller than other BP-lowering supplements.

Key Statistics

7

Estudos

400

Participantes

↑

Positive

C

Nota

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

lcitrulline:
3,000-6,000 mg/day
citrullinemalate:
6,000-8,000 mg/day
bloodpressuresupport:
3,000 mg/day

Limite superior: Not formally established; well-tolerated up to 15,000 mg/day in clinical trials

Melhor horário: On empty stomach; divide doses for sustained arginine elevation

Safety & Side Effects

Efeitos Colaterais Relatados

  • ⚠ Generally well-tolerated
  • ⚠ Mild gastrointestinal discomfort at high doses
  • ⚠ Heartburn (rare)

Interações Conhecidas

  • ● Antihypertensives (additive blood pressure lowering)
  • ● PDE5 inhibitors (excessive vasodilation risk)
  • ● Nitrates (excessive vasodilation risk)

Ingestão máxima tolerável: Not formally established; well-tolerated up to 15,000 mg/day in clinical trials

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does L-Citrulline help with High Blood Pressure (Hypertension)?
Based on 7 studies with 400 participants, there is limited but promising evidence that L-Citrulline may support High Blood Pressure (Hypertension) management. Our evidence grade is C (Some Evidence).
How much L-Citrulline should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 3,000-6,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of L-Citrulline?
Reported side effects may include Generally well-tolerated, Mild gastrointestinal discomfort at high doses, Heartburn (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for L-Citrulline and High Blood Pressure (Hypertension)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 7 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

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        Aviso Legal da FDA:
        Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.