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L-Citrulline untuk High Blood Pressure (Hypertension)

C

Systolic -4.1 mmHg in meta-analysis. May have superior pharmacokinetics vs. arginine for sustained nitric oxide production. Growing evidence base but still smaller than other BP-lowering supplements.

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Kesimpulan

            
            
Systolic -4.1 mmHg in meta-analysis. May have superior pharmacokinetics vs. arginine for sustained nitric oxide production. Growing evidence base but still smaller than other BP-lowering supplements.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
7

        
Studi

    

    

        
400

        
Peserta

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Peringkat

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosis yang Umum Digunakan

                

                    
                    

                        
lcitrulline:

                        
3,000-6,000 mg/day

                    

                    
                    

                        
citrullinemalate:

                        
6,000-8,000 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
3,000 mg/day

                    

                    
                

                
                

                    Batas atas: Not formally established; well-tolerated up to 15,000 mg/day in clinical trials
                

                
            

            

            

            
            

                Waktu terbaik diminum: On empty stomach; divide doses for sustained arginine elevation
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Efek Samping yang Dilaporkan

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
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                            ⚠
                            Mild gastrointestinal discomfort at high doses
                        
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                            ⚠
                            Heartburn (rare)
                        
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Interaksi yang Diketahui

                    
    
                        
                        
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                            ●
                            Antihypertensives (additive blood pressure lowering)
                        
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  • 
                            ●
                            PDE5 inhibitors (excessive vasodilation risk)
                        
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                            ●
                            Nitrates (excessive vasodilation risk)
                        
    • 
                        
                    

                

                

                
                

                    

                        Asupan atas yang dapat ditoleransi: Not formally established; well-tolerated up to 15,000 mg/day in clinical trials
                    

                

                
            

            

                Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does L-Citrulline help with High Blood Pressure (Hypertension)?
            
        
        

            Based on 7 studies with 400 participants, there is limited but promising evidence that L-Citrulline may support High Blood Pressure (Hypertension) management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much L-Citrulline should I take for High Blood Pressure (Hypertension)?
            
        
        

            Studies have used various dosages. A commonly studied range is 3,000-6,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of L-Citrulline?
            
        
        

            Reported side effects may include Generally well-tolerated, Mild gastrointestinal discomfort at high doses, Heartburn (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for L-Citrulline and High Blood Pressure (Hypertension)?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 7 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

        Penafian FDA:
        Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.