Magnesium untuk High Blood Pressure (Hypertension)

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Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

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Kesimpulan

Key Study Findings

Review

Dietary supplements and prevention of preeclampsia.

Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction Efek: ~50% risk reduction None

Populasi: Pregnant women with low calcium intake

Case Reports 13.0 weeks

A case report of Gitelman syndrome in children.

Dose: 3 g vs: None Outcome: pain reduction Efek: None None

Populasi: Hypokalemia

Review

Nutritional prevention of cognitive decline and dementia.

Dose: None vs: None Outcome: Cognitive decline prevention Efek: None None

Populasi: Older adults at risk of cognitive decline

Systematic Review

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on …

Dose: varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements vs: Placebo Efek: None None

Review

Prevention of hypokalemia caused by diuretics.

Dose: None vs: None Outcome: mineral status Efek: None None

Populasi: hypertensive patients

Randomized Controlled Trial n=48 26.0 weeks

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for …

Dose: 100 mg/d vs: control group Outcome: blood pressure Efek: None None

Populasi: hypertensive patients

Key Statistics

Studi

2028

Peserta

↑

Positive

Peringkat

Referenced Papers

Dietary supplements and prevention of preeclampsia. Review

Hypertension research : … 2025 10 sitasi

A case report of Gitelman syndrome in children. Case Report

Medicine 2023

Nutritional prevention of cognitive decline and dementia. Review

Acta bio-medica : … 2018 103 sitasi

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … Systematic Review

JBI database of … 2017 38 sitasi

Prevention of hypokalemia caused by diuretics. Review

Heart disease and … 1994

Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … RCT

European journal of … 1986 22 sitasi

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosis yang Umum Digunakan

general:: 310-420 mg/day
bloodpressuresupport:: 300-500 mg/day
cardiovascularsupport:: 300-400 mg/day elemental magnesium

Batas atas: 350 mg/day from supplements only (no UL for food magnesium)

Dosis yang Diteliti dalam Penelitian

Dosis	Durasi	Efek	N
500 mg daily	--	Positive	--
3 g	13.0 weeks	Mixed	--
None	--	Mixed	--
varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements	--	Mixed	--
None	--	Mixed	--
100 mg/d	26.0 weeks	Mixed	48

Waktu terbaik diminum: With meals to reduce GI side effects; evening dosing may support sleep

Safety & Side Effects

Efek Samping yang Dilaporkan

⚠ Diarrhea (especially magnesium oxide and citrate)
⚠ Nausea
⚠ Abdominal cramping
⚠ Excessive doses may cause hypotension or cardiac depression

Interaksi yang Diketahui

● Bisphosphonates (reduced absorption — separate by 2 hours)
● Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
● Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
● Proton pump inhibitors (long-term use may cause hypomagnesemia)

Asupan atas yang dapat ditoleransi: 350 mg/day from supplements only (no UL for food magnesium)

Selalu konsultasikan dengan tenaga kesehatan Anda sebelum memulai suplemen apa pun.Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai suplemen apa pun.

Frequently Asked Questions

Does Magnesium help with High Blood Pressure (Hypertension)?

Based on 34 studies with 2,028 participants, there is moderate evidence from clinical studies that Magnesium may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).

How much Magnesium should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Magnesium?

Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Magnesium and High Blood Pressure (Hypertension)?

We rate the evidence as Grade B (Good Evidence). This rating is based on 34 peer-reviewed studies with 2,028 total participants. The overall direction of effect is positive.

Bahan lain untuk High Blood Pressure (Hypertension)

Beetroot Extract A Garlic A Potassium B Quercetin B Grape Seed Extract B Coenzyme Q10 (CoQ10) B

Magnesium untuk kondisi lain

Cardiac Arrhythmia B Coronary Artery Disease (CAD) C

Kesimpulan Singkat

Evidence Strength72%

High confidence

Rincian Studi

RCT (1)Meta (0)Other (33)

Bandingkan Alternatif

Lihat bagaimana bahan lain dibandingkan untuk kondisi ini.

Lihat semua bahan untuk High Blood Pressure (Hypertension)

Pelajari Lebih Lanjut

References

[1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
[2] Jing Ying et al.. Medicine (Baltimore). 2023. A case report of Gitelman syndrome in children. doi:10.1097/MD.0000000000033509 PubMed
[3] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed
[4] Delia McCabe et al.. JBI Database System Rev Implement Rep. 2017. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … doi:10.11124/JBISRIR-2016-002965 PubMed
[5] E Bourke et al.. Heart Dis Stroke. 1994. Prevention of hypokalemia caused by diuretics. PubMed
[6] T Dyckner et al.. Eur J Clin Pharmacol. 1986. Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … doi:10.1007/BF00542411 PubMed

Penafian FDA: Pernyataan-pernyataan ini belum dievaluasi oleh Food and Drug Administration. Produk dan informasi di situs web ini tidak dimaksudkan untuk mendiagnosis, mengobati, menyembuhkan, atau mencegah penyakit apa pun. Peringkat bukti yang disajikan didasarkan pada analisis kami terhadap penelitian yang ditinjau sejawat dan tidak merupakan saran medis. Selalu konsultasikan dengan penyedia layanan kesehatan Anda sebelum memulai regimen suplemen apa pun.

Magnesium untuk High Blood Pressure (Hypertension)

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Kesimpulan

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Dosis yang Umum Digunakan

Dosis yang Diteliti dalam Penelitian

Safety & Side Effects

Efek Samping yang Dilaporkan

Interaksi yang Diketahui

Frequently Asked Questions

Related Evidence

Bahan lain untuk High Blood Pressure (Hypertension)

Magnesium untuk kondisi lain

References