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HeartCited

Lycopene für High Blood Pressure (Hypertension)

B Evidenz Mindestens eine randomisierte Studie unterstützt dies, mit überwiegend konsistenten Ergebnissen.

Meta-analysis of 6 RCTs: systolic -5.6 mmHg. Improved endothelial function. Cooking with oil enhances absorption 2-3x. Strong observational associations with lower MI risk.

B

Fazit

Meta-analysis of 6 RCTs: systolic -5.6 mmHg. Improved endothelial function. Cooking with oil enhances absorption 2-3x. Strong observational associations with lower MI risk.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily vs.: Placebo Outcome: Preeclampsia risk reduction Wirkung: ~50% risk reduction

Population: Pregnant women with low calcium intake

Key Statistics

6

Studien

400

Teilnehmer

↑

Positive

B

Bewertung

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:
6-15 mg/day
cardiovascularsupport:
15-30 mg/day

Obergrenze: Not formally established; up to 75 mg/day used in clinical trials

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
500 mg daily -- Positive --

Beste Einnahmezeit: With meals containing fat (cooking with olive oil enhances absorption 2-3x)

Safety & Side Effects

Gemeldete Nebenwirkungen

  • ⚠ Generally well-tolerated
  • ⚠ Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible

Bekannte Wechselwirkungen

  • ● Blood pressure medications (may have mild additive effect)
  • ● Beta-carotene (may compete for absorption)

Tolerierbare Höchstaufnahmemenge: Not formally established; up to 75 mg/day used in clinical trials

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Lycopene help with High Blood Pressure (Hypertension)?
Based on 6 studies with 400 participants, there is moderate evidence from clinical studies that Lycopene may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Lycopene should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 6-15 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Lycopene?
Reported side effects may include Generally well-tolerated, Lycopenodermia (orange skin discoloration) at very high intake — harmless and reversible. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Lycopene and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

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References

  1. [1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
  2. [2] Xiaoran Liu et al.. Am J Clin Nutr. 2025. Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled … doi:10.1016/j.ajcnut.2025.08.012 PubMed
  3. [3] Sitong Wan et al.. Nutrients. 2024. Antioxidant Lipid Supplement on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis. doi:10.3390/nu16142213 PubMed

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