Calcium für High Blood Pressure (Hypertension)

C Evidenz Begrenzte Evidenz aus kleinen Studien, aber es gibt einige positive Signale.

Small meta-analytic BP reduction (-1.4 mmHg systolic). Overwhelmed by cardiovascular safety concerns from supplement studies. Dietary calcium preferred.

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Fazit

Small meta-analytic BP reduction (-1.4 mmHg systolic). Overwhelmed by cardiovascular safety concerns from supplement studies. Dietary calcium preferred.

Key Study Findings

Meta-Analysis

Associations between Diet and Cognitive Function in Stroke Survivors: A Systematic Review and Meta-analysis.

Dose: None vs.: Standard care or placebo Outcome: Global cognition in stroke survivors Wirkung: SMD=0.62 (energy-protein); SMD=-0.40 (B-vitamins) 0.009 (protein); 0.02 (B-vit)

Population: Adult stroke survivors (20 trials + 14 observational)

Review

Dietary supplements and prevention of preeclampsia.

Dose: 500 mg daily vs.: Placebo Outcome: Preeclampsia risk reduction Wirkung: ~50% risk reduction None

Population: Pregnant women with low calcium intake

Review

Novel pharmacologic approaches in resistant hypertension.

Dose: Spironolactone, sacubitril/valsartan, SGLT2i vs.: None Outcome: Blood pressure control in resistant HTN Wirkung: None None

Population: Patients with resistant hypertension

Review

Vegan Diet Health Benefits in Metabolic Syndrome.

Dose: None vs.: None Outcome: None Wirkung: None None

Population: Adults with metabolic syndrome

cross-sectional observational study n=260

Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers.

Dose: None vs.: Placebo Wirkung: None None

Observational Study n=40

Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1).

Dose: anti-digoxin antibodies (Fab) vs.: pre-treatment Outcome: serum digoxin and clinical outcomes Wirkung: Fab bound digoxin; no improved clinical outcomes None

Population: Chronic digoxin toxicity patients

Key Statistics

Studien

1500

Teilnehmer

↔

Mixed

Bewertung

Referenced Papers

Dietary supplements and prevention of preeclampsia. Review

Hypertension research : … 2025 10 Zitierungen

Associations between Diet and Cognitive Function in Stroke Survivors: A Systematic Review and Meta-analysis. Meta-Analysis

Advances in nutrition … 2025 1 Zitierungen

Novel pharmacologic approaches in resistant hypertension. Review

Wiadomosci lekarskie (Warsaw, … 2024

Vegan Diet Health Benefits in Metabolic Syndrome. Review

Nutrients 2021 113 Zitierungen

Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers. Other

Journal of renal … 2017 26 Zitierungen

Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1). Observational

Clinical toxicology (Philadelphia, … 2016 25 Zitierungen

Emerging concepts for patients with treatment-resistant hypertension. Review

Trends in cardiovascular … 2016 19 Zitierungen

Restless leg syndrome: a neglected diagnosis. Review

Nephro-urology monthly 2014 43 Zitierungen

[Clinical characteristics and combined use of medicine analysis of 2 991 hospitalized patients with psoriasis based on real world database]. Other

Zhongguo Zhong yao … 2014 4 Zitierungen

Vitamin D in health and disease: a literature review. Review

British journal of … 2013 156 Zitierungen

Vitamin D and autoimmune disease. Review

Acta medica Indonesiana 2007 4 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

note:: Prefer dietary sources; limit supplements to 500 mg/dose
general:: 1,000-1,200 mg/day from diet plus supplements

Obergrenze: 2,000-2,500 mg/day (total from diet and supplements)

In der Forschung untersuchte Dosierungen

Dosierung	Dauer	Wirkung	N
None	--	Mixed	--
500 mg daily	--	Positive	--
Spironolactone, sacubitril/valsartan, SGLT2i	--	Positive	--
None	--	Mixed	--
None	--	Neutral	260
anti-digoxin antibodies (Fab)	--	Neutral	40
None	--	Mixed	--
None	--	Neutral	2991

Beste Einnahmezeit: Divide doses (500 mg max per dose); carbonate with meals; citrate any time

Safety & Side Effects

Gemeldete Nebenwirkungen

⚠ Constipation (especially carbonate form)
⚠ Potential increased MI risk with high-dose supplements (controversial)
⚠ Kidney stones at excessive doses
⚠ Gas, bloating

Bekannte Wechselwirkungen

● Thyroid medications (separate by 4 hours)
● Bisphosphonates (separate by 30-60 minutes)
● Iron supplements (reduced absorption — separate by 2 hours)
● Certain antibiotics (reduced absorption)
● Vitamin K2 (may help direct supplemental calcium to bones, not arteries)

Tolerierbare Höchstaufnahmemenge: 2,000-2,500 mg/day (total from diet and supplements)

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Calcium help with High Blood Pressure (Hypertension)?

Based on 13 studies with 1,500 participants, there is limited but promising evidence that Calcium may support High Blood Pressure (Hypertension) management. Our evidence grade is C (Some Evidence).

How much Calcium should I take for High Blood Pressure (Hypertension)?

Studies have used various dosages. A commonly studied range is Prefer dietary sources; limit supplements to 500 mg/dose. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Calcium?

Reported side effects may include Constipation (especially carbonate form), Potential increased MI risk with high-dose supplements (controversial), Kidney stones at excessive doses, Gas, bloating. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Calcium and High Blood Pressure (Hypertension)?

We rate the evidence as Grade C (Some Evidence). This rating is based on 13 peer-reviewed studies with 1,500 total participants. The overall direction of effect is mixed.

Andere Inhaltsstoffe für High Blood Pressure (Hypertension)

Beetroot Extract A Garlic A Magnesium B Potassium B Quercetin B Grape Seed Extract B

Kurzfazit

Small meta-analytic BP reduction (-1.4 mmHg systolic). Overwhelmed by cardiovascular safety concerns from supplement studies. Dietary calcium preferred.

Evidence Strength52%

Moderate confidence

Studienübersicht

RCT (0)Meta (1)Other (12)

Alternativen vergleichen

Sehen Sie, wie andere Inhaltsstoffe bei dieser Beschwerde abschneiden.

Alle Inhaltsstoffe ansehen für High Blood Pressure (Hypertension)

Mehr erfahren

References

[1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
[2] Sasan Amanat et al.. Adv Nutr. 2025. Associations between Diet and Cognitive Function in Stroke Survivors: A Systematic Review and Meta-analysis. doi:10.1016/j.advnut.2025.100440 PubMed
[3] Jerzy Głuszek. Wiad Lek. 2024. Novel pharmacologic approaches in resistant hypertension. doi:10.36740/WLek/194090 PubMed
[4] Giulia Marrone et al.. Nutrients. 2021. Vegan Diet Health Benefits in Metabolic Syndrome. doi:10.3390/nu13030817 PubMed
[5] Niloufar Zadeh Saraji et al.. J Renal Inj Prev. 2017. Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers. doi:10.15171/jrip.2017.27 PubMed
[6] Betty S Chan et al.. Clin Toxicol (Phila). 2016. Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1). doi:10.1080/15563650.2016.1175620 PubMed
[7] Alfonso Eirin et al.. Trends Cardiovasc Med. 2016. Emerging concepts for patients with treatment-resistant hypertension. doi:10.1016/j.tcm.2016.05.004 PubMed
[8] Behzad Einollahi et al.. Nephrourol Mon. 2014. Restless leg syndrome: a neglected diagnosis. doi:10.5812/numonthly.22009 PubMed
[9] Jian-hong Li et al.. Zhongguo Zhong Yao Za Zhi. 2014. [Clinical characteristics and combined use of medicine analysis of 2 991 hospitalized patients with psoriasis based on real world database]. PubMed
[10] S Basit. Br J Biomed Sci. 2013. Vitamin D in health and disease: a literature review. doi:10.1080/09674845.2013.11669951 PubMed
[11] Eka Ginanjar et al.. Acta Med Indones. 2007. Vitamin D and autoimmune disease. PubMed

FDA-Haftungsausschluss: Diese Aussagen wurden nicht von der Food and Drug Administration bewertet. Die Produkte und Informationen auf dieser Website sind nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Die dargestellten Evidenzbewertungen basieren auf unserer Analyse veröffentlichter begutachteter Forschung und stellen keine medizinische Beratung dar. Konsultieren Sie immer Ihren Arzt, bevor Sie mit der Einnahme von Nahrungsergänzungsmitteln beginnen.

Calcium für High Blood Pressure (Hypertension)

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Fazit

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

Übliche Dosierungen

In der Forschung untersuchte Dosierungen

Safety & Side Effects

Gemeldete Nebenwirkungen

Bekannte Wechselwirkungen

Frequently Asked Questions

Related Evidence

Andere Inhaltsstoffe für High Blood Pressure (Hypertension)

References