Calcium के लिए High Blood Pressure (Hypertension)
C साक्ष्य की तुलना करें छोटे अध्ययनों से सीमित साक्ष्य उपलब्ध हैं, लेकिन कुछ सकारात्मक संकेत मौजूद हैं।Small meta-analytic BP reduction (-1.4 mmHg systolic). Overwhelmed by cardiovascular safety concerns from supplement studies. Dietary calcium preferred.
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C
निष्कर्ष
Small meta-analytic BP reduction (-1.4 mmHg systolic). Overwhelmed by cardiovascular safety concerns from supplement studies. Dietary calcium preferred.
Key Study Findings
Meta-Analysis
Associations between Diet and Cognitive Function in Stroke Survivors: A Systematic Review and Meta-analysis.
Dose: None
बनाम: Standard care or placebo
Outcome: Global cognition in stroke survivors
प्रभाव: SMD=0.62 (energy-protein); SMD=-0.40 (B-vitamins)
0.009 (protein); 0.02 (B-vit)
जनसंख्या: Adult stroke survivors (20 trials + 14 observational)
Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily
बनाम: Placebo
Outcome: Preeclampsia risk reduction
प्रभाव: ~50% risk reduction
None
जनसंख्या: Pregnant women with low calcium intake
Review
Novel pharmacologic approaches in resistant hypertension.
Dose: Spironolactone, sacubitril/valsartan, SGLT2i
बनाम: None
Outcome: Blood pressure control in resistant HTN
प्रभाव: None
None
जनसंख्या: Patients with resistant hypertension
Review
Vegan Diet Health Benefits in Metabolic Syndrome.
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: Adults with metabolic syndrome
cross-sectional observational study
n=260
Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers.
Dose: None
बनाम: Placebo
प्रभाव: None
None
Observational Study
n=40
Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1).
Dose: anti-digoxin antibodies (Fab)
बनाम: pre-treatment
Outcome: serum digoxin and clinical outcomes
प्रभाव: Fab bound digoxin; no improved clinical outcomes
None
जनसंख्या: Chronic digoxin toxicity patients
Key Statistics
13
अध्ययन
1500
प्रतिभागी
↔
Mixed
C
ग्रेड
Referenced Papers
Hypertension research : …
2025
10 उद्धरण
Associations between Diet and Cognitive Function in Stroke Survivors: A Systematic Review and Meta-analysis.
Meta-Analysis
Advances in nutrition …
2025
1 उद्धरण
Wiadomosci lekarskie (Warsaw, …
2024
Nutrients
2021
113 उद्धरण
Journal of renal …
2017
26 उद्धरण
Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1).
Observational
Clinical toxicology (Philadelphia, …
2016
25 उद्धरण
Trends in cardiovascular …
2016
19 उद्धरण
Nephro-urology monthly
2014
43 उद्धरण
Zhongguo Zhong yao …
2014
4 उद्धरण
British journal of …
2013
156 उद्धरण
Acta medica Indonesiana
2007
4 उद्धरण
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- note:
- Prefer dietary sources; limit supplements to 500 mg/dose
- general:
- 1,000-1,200 mg/day from diet plus supplements
अधिकतम सीमा: 2,000-2,500 mg/day (total from diet and supplements)
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| 500 mg daily | -- | Positive | -- |
| Spironolactone, sacubitril/valsartan, SGLT2i | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | 260 |
| anti-digoxin antibodies (Fab) | -- | Neutral | 40 |
| None | -- | Mixed | -- |
| None | -- | Neutral | 2991 |
सेवन का सर्वोत्तम समय: Divide doses (500 mg max per dose); carbonate with meals; citrate any time
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ Constipation (especially carbonate form)
- ⚠ Potential increased MI risk with high-dose supplements (controversial)
- ⚠ Kidney stones at excessive doses
- ⚠ Gas, bloating
ज्ञात अंतःक्रियाएँ
- ● Thyroid medications (separate by 4 hours)
- ● Bisphosphonates (separate by 30-60 minutes)
- ● Iron supplements (reduced absorption — separate by 2 hours)
- ● Certain antibiotics (reduced absorption)
- ● Vitamin K2 (may help direct supplemental calcium to bones, not arteries)
सहनीय अधिकतम सेवन: 2,000-2,500 mg/day (total from diet and supplements)
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Calcium help with High Blood Pressure (Hypertension)?
Based on 13 studies with 1,500 participants, there is limited but promising evidence that Calcium may support High Blood Pressure (Hypertension) management. Our evidence grade is C (Some Evidence).
How much Calcium should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is Prefer dietary sources; limit supplements to 500 mg/dose. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Calcium?
Reported side effects may include Constipation (especially carbonate form), Potential increased MI risk with high-dose supplements (controversial), Kidney stones at excessive doses, Gas, bloating. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Calcium and High Blood Pressure (Hypertension)?
We rate the evidence as Grade C (Some Evidence). This rating is based on 13 peer-reviewed studies with 1,500 total participants. The overall direction of effect is mixed.
Related Evidence
इसके लिए अन्य सामग्री High Blood Pressure (Hypertension)
References
- [1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
- [2] Sasan Amanat et al.. Adv Nutr. 2025. Associations between Diet and Cognitive Function in Stroke Survivors: A Systematic Review and Meta-analysis. doi:10.1016/j.advnut.2025.100440 PubMed
- [3] Jerzy Głuszek. Wiad Lek. 2024. Novel pharmacologic approaches in resistant hypertension. doi:10.36740/WLek/194090 PubMed
- [4] Giulia Marrone et al.. Nutrients. 2021. Vegan Diet Health Benefits in Metabolic Syndrome. doi:10.3390/nu13030817 PubMed
- [5] Niloufar Zadeh Saraji et al.. J Renal Inj Prev. 2017. Restless leg syndrome in chronic hemodialysis patients in Mashhad hemodialysis centers. doi:10.15171/jrip.2017.27 PubMed
- [6] Betty S Chan et al.. Clin Toxicol (Phila). 2016. Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1). doi:10.1080/15563650.2016.1175620 PubMed
- [7] Alfonso Eirin et al.. Trends Cardiovasc Med. 2016. Emerging concepts for patients with treatment-resistant hypertension. doi:10.1016/j.tcm.2016.05.004 PubMed
- [8] Behzad Einollahi et al.. Nephrourol Mon. 2014. Restless leg syndrome: a neglected diagnosis. doi:10.5812/numonthly.22009 PubMed
- [9] Jian-hong Li et al.. Zhongguo Zhong Yao Za Zhi. 2014. [Clinical characteristics and combined use of medicine analysis of 2 991 hospitalized patients with psoriasis based on real world database]. PubMed
- [10] S Basit. Br J Biomed Sci. 2013. Vitamin D in health and disease: a literature review. doi:10.1080/09674845.2013.11669951 PubMed
- [11] Eka Ginanjar et al.. Acta Med Indones. 2007. Vitamin D and autoimmune disease. PubMed
FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।