Skip to main content
HeartCited

Vitamin E
Vitamin E

vitamin

다른 이름: Alpha-Tocopherol, d-Alpha-Tocopherol, Mixed Tocopherols, Tocotrienols

<\/script>\n
`; }, get iframeSnippet() { const domain = 'heartcited.com'; const params = 'ingredient\u003Dvitamin\u002De'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  




    






    
    

        
        
        

            

  
About





            

                
Vitamin E is the primary lipid-soluble antioxidant in LDL particles and cell membranes. Despite strong mechanistic rationale, large RCTs have been disappointing. The HOPE trial (9,541 participants) found no cardiovascular benefit at 400 IU/day, and a 2005 meta-analysis found high-dose vitamin E (>=400 IU/day) was associated with increased all-cause mortality. Current AHA guidelines do not recommend vitamin E supplementation.

            

        

        

        
        
        

            

  
How It Works





            

                
Primary lipid-soluble antioxidant in LDL particles and cell membranes; inhibits LDL oxidation — a key early step in atherogenesis; modulates inflammatory gene expression via NF-kB inhibition; inhibits platelet adhesion and smooth muscle cell proliferation.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                건강 상태
                                등급
                                연구
                                참여자
                                
                            

                        
                        
                            
                            

                                
                                    
                                        Atherosclerosis
                                    
                                
                                
                                    C

                                
                                
                                    15
                                
                                
                                    50000
                                
                                
                                    
                                        보기 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
  • 
                    
                    Increased bleeding risk at high doses
                
    • 
                
                
  • 
                    
                    Possible increased all-cause mortality at >=400 IU/day
                
    • 
                
                
  • 
                    
                    Increased heart failure hospitalization risk (HOPE/HOPE-TOO)
                
    • 
                
                
  • 
                    
                    Nausea, diarrhea, fatigue at high doses
                
    • 
                
            

        

        

        
        
        

            

  
Drug & Supplement Interactions





            
    
                
                
  • 
                    
                    Anticoagulants (increased bleeding risk)
                
    • 
                
                
  • 
                    
                    Statins and niacin (may blunt HDL-raising effect)
                
    • 
                
                
  • 
                    
                    Chemotherapy and radiation (theoretical interference with oxidative mechanisms)
                
    • 
                
                
  • 
                    
                    Vitamin K (may antagonize at high doses)
                
    • 
                
            

            

                복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Vitamin D
                    
                
                
                
                    Vitamin K2
                    
                
                
                
                    Niacin (Vitamin B3)
                    
                
                
                
                    Folate (Vitamin B9)
                    
                
                
            

        

        
    


    
    












    

        FDA 면책 조항:
        이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.