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L-Arginine 관련 Heart Failure

D

Small studies show improved exercise capacity. However, safety concerns from the VINTAGE MI trial apply to the broader acute cardiac population. Use with caution.

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D

결론

Small studies show improved exercise capacity. However, safety concerns from the VINTAGE MI trial apply to the broader acute cardiac population. Use with caution.

Key Statistics

3

연구

150

참여자

Mixed

D

등급

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

endothelialfunction:
3,000-6,000 mg/day
bloodpressuresupport:
6,000-10,000 mg/day divided BID-TID

상한량: Not formally established; GI discomfort common above 10,000 mg/day

권장 복용 시간: On empty stomach for best absorption; divide doses throughout the day

Safety & Side Effects

보고된 부작용

  • Gastrointestinal discomfort (nausea, diarrhea, bloating)
  • Hypotension at high doses
  • Worsening of herpes simplex (arginine promotes viral replication)
  • Potential harm in acute post-MI patients (VINTAGE MI concern)

알려진 상호작용

  • Antihypertensives (additive blood pressure lowering)
  • PDE5 inhibitors (sildenafil — excessive vasodilation risk)
  • Nitrates (excessive vasodilation risk)
  • Anticoagulants (may have mild antiplatelet effect)
  • Potassium-sparing diuretics (arginine may increase potassium levels)

일일 최대 섭취 허용량: Not formally established; GI discomfort common above 10,000 mg/day

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does L-Arginine help with Heart Failure?
Based on 3 studies with 150 participants, there is preliminary evidence that needs more research that L-Arginine may support Heart Failure management. Our evidence grade is D (Very Early Research).
How much L-Arginine should I take for Heart Failure?
Studies have used various dosages. A commonly studied range is 3,000-6,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of L-Arginine?
Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, bloating), Hypotension at high doses, Worsening of herpes simplex (arginine promotes viral replication), Potential harm in acute post-MI patients (VINTAGE MI concern). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for L-Arginine and Heart Failure?
We rate the evidence as Grade D (Very Early Research). This rating is based on 3 peer-reviewed studies with 150 total participants. The overall direction of effect is mixed.

Related Evidence

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.