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Resveratrol 用于 High Blood Pressure (Hypertension)

B

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

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            B

        

        

            
结论

            
            
Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
10

        
研究数量

    

    

        
600

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
等级

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
150-500 mg/day

                    

                    
                    

                        
cardiovascularsupport:

                        
250-500 mg/day trans-resveratrol

                    

                    
                

                
                

                    上限： Not formally established; GI discomfort common above 1,000 mg/day
                

                
            

            

            

            
            

                最佳服用时间： With meals; bioavailability enhanced by piperine co-supplementation
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                        
  • 
                            ⚠
                            May have estrogenic activity at high doses
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may inhibit platelet aggregation)
                        
    • 
                        
                        
  • 
                            ●
                            CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
                        
    • 
                        
                        
  • 
                            ●
                            Blood pressure medications (additive hypotensive effect)
                        
    • 
                        
                        
  • 
                            ●
                            Estrogen-sensitive conditions (weak estrogenic activity)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not formally established; GI discomfort common above 1,000 mg/day
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Resveratrol help with High Blood Pressure (Hypertension)?
            
        
        

            Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Resveratrol should I take for High Blood Pressure (Hypertension)?
            
        
        

            Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Resveratrol?
            
        
        

            Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Resveratrol 用于其他健康状况

                    

                        
                        
                            Atherosclerosis
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

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