Resveratrol 用于高血压

Q: Does Resveratrol help with 高血压?

Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support 高血压 management. Our evidence grade is B (Good Evidence).

Q: How much Resveratrol should I take for 高血压?

Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Resveratrol?

Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Resveratrol and 高血压?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

B 证据至少一项随机试验支持这一结论，结果基本一致。

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

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结论

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Key Study Findings

Review

Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk.

Dose: None vs: None Outcome: None 效果: None None

研究人群: review of nutrition and lifestyle interventions for dyslipidemia and cardiometabolic risk

Review

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.

Dose: None vs: None Outcome: None 效果: None None

研究人群: review of age-related cardiac dysfunction and heart failure mechanisms

Review

Dietary supplements and prevention of preeclampsia.

Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction 效果: ~50% risk reduction None

研究人群: Pregnant women with low calcium intake

Systematic Review

The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.

Dose: None vs: Placebo or no treatment Outcome: Cardiometabolic changes in menopausal women 效果: None None

研究人群: Menopausal women

Controlled Clinical Trial

Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway.

Dose: None vs: Model group (no RES) and sham control Outcome: Cerebral aneurysm formation 效果: None P<0.05

研究人群: Mice with induced hypertension CA model

Review

The Role of Resveratrol Administration in Human Obesity.

Dose: None vs: None Outcome: None 效果: None None

研究人群: Obese adults

Key Statistics

研究数量

600

受试者

↑

Positive

等级

Referenced Papers

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. Review

ESC heart failure 2025 58 次引用

Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. Review

Nutrients 2025 32 次引用

Dietary supplements and prevention of preeclampsia. Review

Hypertension research : … 2025 10 次引用

The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. Other

Cardiovascular & hematological … 2025

Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. Other

Acta biochimica Polonica 2022 10 次引用

The Role of Resveratrol Administration in Human Obesity. Review

International journal of … 2021 50 次引用

Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. Other

Nutrients 2020 49 次引用

Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. Other

Nutrients 2020 16 次引用

Nutritional prevention of cognitive decline and dementia. Review

Acta bio-medica : … 2018 103 次引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

常用剂量

general:: 150-500 mg/day
cardiovascularsupport:: 250-500 mg/day trans-resveratrol

上限： Not formally established; GI discomfort common above 1,000 mg/day

研究中使用的剂量

剂量	持续时间	效果	N
None	--	Positive	--
None	--	Neutral	--
500 mg daily	--	Positive	--
None	--	Positive	--
None	--	Positive	--
None	--	Mixed	--
75 mg	14 weeks	Positive	129
None	--	Mixed	--

最佳服用时间： With meals; bioavailability enhanced by piperine co-supplementation

Safety & Side Effects

已报告的副作用

⚠ Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
⚠ Headache
⚠ May have estrogenic activity at high doses

已知相互作用

● Anticoagulants (may inhibit platelet aggregation)
● CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
● Blood pressure medications (additive hypotensive effect)
● Estrogen-sensitive conditions (weak estrogenic activity)

可耐受最高摄入量： Not formally established; GI discomfort common above 1,000 mg/day

在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。

Frequently Asked Questions

Does Resveratrol help with 高血压?

Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support 高血压 management. Our evidence grade is B (Good Evidence).

How much Resveratrol should I take for 高血压?

Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Resveratrol?

Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Resveratrol and 高血压?

We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

其他成分用于高血压

Beetroot Extract A Garlic A Magnesium B Potassium B Quercetin B Grape Seed Extract B

Resveratrol 用于其他健康状况

动脉粥样硬化 C

快速结论

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Evidence Strength72%

High confidence

研究分析

RCT (0)Meta (0)Other (10)

对比替代方案

查看其他成分针对该健康状况的对比结果。

查看所有成分用于高血压

了解更多

References

[1] Zhuyubing Fang et al.. ESC Heart Fail. 2025. Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. doi:10.1002/ehf2.14947 PubMed
[2] Hygerta Berisha et al.. Nutrients. 2025. Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. doi:10.3390/nu17050776 PubMed
[3] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
[4] Ali Amini et al.. Cardiovasc Hematol Disord Drug Targets. 2025. The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. doi:10.2174/011871529X398468250910225946 PubMed
[5] Tao Jin et al.. Acta Biochim Pol. 2022. Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. doi:10.18388/abp.2020_5982 PubMed
[6] Laura M Mongioì et al.. Int J Mol Sci. 2021. The Role of Resveratrol Administration in Human Obesity. doi:10.3390/ijms22094362 PubMed
[7] Jay Jay Thaung Zaw et al.. Nutrients. 2020. Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. doi:10.3390/nu12030828 PubMed
[8] Raúl Francisco Pastor et al.. Nutrients. 2020. Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. doi:10.3390/nu12103149 PubMed
[9] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed

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Resveratrol 用于 高血压

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结论

Key Study Findings

Key Statistics

Referenced Papers

Dosage & Usage

常用剂量

研究中使用的剂量

Safety & Side Effects

已报告的副作用

已知相互作用

Frequently Asked Questions

Related Evidence

其他成分用于 高血压

Resveratrol 用于其他健康状况

References

Resveratrol 用于高血压

其他成分用于高血压