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Hawthorn 用于 高血压

C 证据 来自小型研究的证据有限，但存在一些积极信号。

Some studies show modest BP reduction as secondary outcome in heart failure trials. Dedicated hypertension trials are limited. ACE-inhibitory mechanism is plausible.

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            C

        

        

            
结论

            
            
Some studies show modest BP reduction as secondary outcome in heart failure trials. Dedicated hypertension trials are limited. ACE-inhibitory mechanism is plausible.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                Supplements for Lipid Lowering: What Does the Evidence Show?
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: lipid levels
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: None

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
4

        
研究数量

    

    

        
300

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Supplements for Lipid Lowering: What Does the Evidence Show?
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Current cardiology reports
                        2023
                        
                        7 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
450-900 mg/day standardized extract (WS 1442 or LI 132)

                    

                    
                    

                        
standardization:

                        
18.75% OPCs or 2.2% flavonoids

                    

                    
                

                
                

                    上限： Not formally established; up to 1,800 mg/day used in the SPICE trial
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： With meals; effects require 6-8 weeks of continuous use
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Dizziness
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea
                        
    • 
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Cardiac glycosides (digoxin — may enhance inotropic effects)
                        
    • 
                        
                        
  • 
                            ●
                            Antihypertensives (additive blood pressure lowering)
                        
    • 
                        
                        
  • 
                            ●
                            Beta-blockers (additive cardiac effects)
                        
    • 
                        
                        
  • 
                            ●
                            PDE5 inhibitors (additive vasodilation)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not formally established; up to 1,800 mg/day used in the SPICE trial
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Hawthorn help with 高血压?
            
        
        

            Based on 4 studies with 300 participants, there is limited but promising evidence that Hawthorn may support 高血压 management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Hawthorn should I take for 高血压?
            
        
        

            Studies have used various dosages. A commonly studied range is 450-900 mg/day standardized extract (WS 1442 or LI 132). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Hawthorn?
            
        
        

            Reported side effects may include Generally well-tolerated, Dizziness, Nausea, Gastrointestinal discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Hawthorn and 高血压?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Hawthorn 用于其他健康状况

                    

                        
                        
                            心力衰竭
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Saeid Mirzai et al..
      Curr Cardiol Rep.
      2023.
      Supplements for Lipid Lowering: What Does the Evidence Show?
      doi:10.1007/s11886-023-01903-9
      PubMed
    
    2. 
    
  















    

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