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Resveratrol 관련 고혈압

B 근거 적어도 하나의 무작위 시험이 이를 지지하며, 대체로 일관된 결과를 보입니다.

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

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결론

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Key Study Findings

Review
Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk.
Dose: None vs: None Outcome: None 효과: None None

대상 집단: review of nutrition and lifestyle interventions for dyslipidemia and cardiometabolic risk

Review
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.
Dose: None vs: None Outcome: None 효과: None None

대상 집단: review of age-related cardiac dysfunction and heart failure mechanisms

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction 효과: ~50% risk reduction None

대상 집단: Pregnant women with low calcium intake

Systematic Review
The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.
Dose: None vs: Placebo or no treatment Outcome: Cardiometabolic changes in menopausal women 효과: None None

대상 집단: Menopausal women

Controlled Clinical Trial
Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway.
Dose: None vs: Model group (no RES) and sham control Outcome: Cerebral aneurysm formation 효과: None P<0.05

대상 집단: Mice with induced hypertension CA model

Review
The Role of Resveratrol Administration in Human Obesity.
Dose: None vs: None Outcome: None 효과: None None

대상 집단: Obese adults

Key Statistics

10

연구

600

참여자

Positive

B

등급

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

general:
150-500 mg/day
cardiovascularsupport:
250-500 mg/day trans-resveratrol

상한량: Not formally established; GI discomfort common above 1,000 mg/day

연구에서 사용된 용량

용량 기간 효과 N
None -- Positive --
None -- Neutral --
500 mg daily -- Positive --
None -- Positive --
None -- Positive --
None -- Mixed --
75 mg 14 weeks Positive 129
None -- Mixed --

권장 복용 시간: With meals; bioavailability enhanced by piperine co-supplementation

Safety & Side Effects

보고된 부작용

  • Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
  • Headache
  • May have estrogenic activity at high doses

알려진 상호작용

  • Anticoagulants (may inhibit platelet aggregation)
  • CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
  • Blood pressure medications (additive hypotensive effect)
  • Estrogen-sensitive conditions (weak estrogenic activity)

일일 최대 섭취 허용량: Not formally established; GI discomfort common above 1,000 mg/day

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does Resveratrol help with 고혈압?
Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support 고혈압 management. Our evidence grade is B (Good Evidence).
How much Resveratrol should I take for 고혈압?
Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Resveratrol?
Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Resveratrol and 고혈압?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Resveratrol 다른 건강 상태에 대한 근거

References

  1. [1] Zhuyubing Fang et al.. ESC Heart Fail. 2025. Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. doi:10.1002/ehf2.14947 PubMed
  2. [2] Hygerta Berisha et al.. Nutrients. 2025. Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. doi:10.3390/nu17050776 PubMed
  3. [3] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
  4. [4] Ali Amini et al.. Cardiovasc Hematol Disord Drug Targets. 2025. The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. doi:10.2174/011871529X398468250910225946 PubMed
  5. [5] Tao Jin et al.. Acta Biochim Pol. 2022. Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. doi:10.18388/abp.2020_5982 PubMed
  6. [6] Laura M Mongioì et al.. Int J Mol Sci. 2021. The Role of Resveratrol Administration in Human Obesity. doi:10.3390/ijms22094362 PubMed
  7. [7] Jay Jay Thaung Zaw et al.. Nutrients. 2020. Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. doi:10.3390/nu12030828 PubMed
  8. [8] Raúl Francisco Pastor et al.. Nutrients. 2020. Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. doi:10.3390/nu12103149 PubMed
  9. [9] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.