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Vitamin D 관련 고혈압

C 근거 소규모 연구에서의 근거는 제한적이지만, 일부 긍정적인 신호가 존재합니다.

Meta-analyses show modest BP reduction (-2-6 mmHg) in deficient populations only. VITAL trial was negative for cardiovascular endpoints. Research suggests benefits may be limited to correcting deficiency.

C

결론

Meta-analyses show modest BP reduction (-2-6 mmHg) in deficient populations only. VITAL trial was negative for cardiovascular endpoints. Research suggests benefits may be limited to correcting deficiency.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily vs: Placebo Outcome: Preeclampsia risk reduction 효과: ~50% risk reduction

대상 집단: Pregnant women with low calcium intake

Systematic Review
Interventions for preventing the progression of autosomal dominant polycystic kidney disease.
Dose: Disease-modifying agents (tolvaptan, etc.) vs: Placebo or standard care Outcome: Kidney disease progression

대상 집단: Patients with ADPKD

Observational Study
Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study.
Dose: 36% Outcome: hair regrowth p < 0.05

대상 집단: Aa referred to our hospitals between 2018 and 2021

cross-sectional observational study n=103
Sleep status in multiple sclerosis: Role of vitamin D and body mass index.
Dose: not applicable vs: Placebo 효과: 37.87% had poor sleep quality; 33.96% had subthreshold or clinical insomnia; sleep status not signif <0.01 (BDI-ISI and BDI-PSQI co
in vitro study
l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 …
Dose: VD 10 nM; LC 250 µM; combined VD+LC vs: Placebo 효과: VD+LC: 46% ROS reduction vs 26% (VD) and 19% (LC) alone; VD+LC: IL-8 inhibition 36% vs 16% (VD alone

Key Statistics

20

연구

30000

참여자

↔

Mixed

C

등급

Referenced Papers

Relationship Between Serum Vitamins and Cognitive Impairment in the Elderly: A Study Based on the NHANES Database. Other
Brain and behavior 2026
Dietary supplements and prevention of preeclampsia. Review
Hypertension research : … 2025 10 인용
Cytomegalovirus (CMV), oxidative stress, and inflammation: implications for immunosenescence and age-related diseases in the MARK-AGE population. Other
Biogerontology 2025
Top studies of 2024 relevant to primary care: From the PEER team. Review
Canadian family physician … 2025
Cardiovascular Risk and Systemic Inflammation in Alopecia Areata: An Observational Case-control Study. Observational
Acta dermatovenerologica Croatica … 2025
Interventions for preventing the progression of autosomal dominant polycystic kidney disease. Systematic Review
The Cochrane database … 2024 1 인용
Effects of age and sex on the comorbidities of alopecia areata: A cross-sectional hospital-based study. Other
Health science reports 2023 3 인용
Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million Participants. Observational
Nutrients 2022 14 인용
Sleep status in multiple sclerosis: Role of vitamin D and body mass index. Other
Current journal of … 2022 11 인용
Sleep patterns modify the association of 25(OH)D with poor cardiovascular health in pregnant women. Other
Frontiers in nutrition 2022 4 인용
Vitamin D levels in primary care patients: correlations with clinical, seasonal, and quality-of-life parameters. Other
Family practice 2022 2 인용
Vegan Diet Health Benefits in Metabolic Syndrome. Review
Nutrients 2021 113 인용
l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 Secretion in High Glucose Treated … Other
Journal of the … 2021 23 인용
Potential of Chlorella as a Dietary Supplement to Promote Human Health. Review
Nutrients 2020 219 인용
Vitamin D deficiency changes the intestinal microbiome reducing B vitamin production in the gut. The resulting lack of pantothenic acid … Other
Medical hypotheses 2016 105 인용
Nutrient intake, nutritional status, and cognitive function with aging. Review
Annals of the … 2016 89 인용
Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Other
International journal of … 2016 28 인용
Vitamin D in health and disease: a literature review. Review
British journal of … 2013 156 인용
Occurrence of milnacipran-associated morbilliform rash and serotonin toxicity. Case Report
The Annals of … 2013
The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and … RCT
Contemporary clinical trials 2012 522 인용
Vitamin D and autoimmune disease. Review
Acta medica Indonesiana 2007 4 인용
Intensive session: New approaches to medical issues in long-term care. Review
Journal of the … 2007
Sleep behavior disorders in a large cohort of chinese (Taiwanese) patients maintained by long-term hemodialysis. Other
American journal of … 2006
Endometrial effects during hormone replacement therapy with a sequential oestradiol valerate/cyproterone acetate preparation. RCT
Maturitas 1993

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

general:
600-800 IU/day
deficiencycorrection:
4,000-5,000 IU/day (under medical supervision)
cardiovascularsupport:
1,000-2,000 IU/day

상한량: 4,000 IU/day (100 mcg)

연구에서 사용된 용량

용량 기간 효과 N
500 mg daily -- Positive --
Disease-modifying agents (tolvaptan, etc.) -- Positive --
36% -- Mixed --
not applicable -- Neutral 103
VD 10 nM; LC 250 µM; combined VD+LC -- Positive --

권장 복용 시간: With a meal containing fat for better absorption

Safety & Side Effects

보고된 부작용

  • ⚠ Hypercalcemia at very high doses (fatigue, nausea, kidney stones)
  • ⚠ Constipation
  • ⚠ Generally very safe at recommended doses

알려진 상호작용

  • ● Thiazide diuretics (may increase hypercalcemia risk)
  • ● Statins (theoretical interaction via CYP enzymes)
  • ● Corticosteroids (may reduce vitamin D absorption)
  • ● Weight loss medications (may reduce absorption of fat-soluble vitamins)

일일 최대 섭취 허용량: 4,000 IU/day (100 mcg)

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does Vitamin D help with 고혈압?
Based on 20 studies with 30,000 participants, there is limited but promising evidence that Vitamin D may support 고혈압 management. Our evidence grade is C (Some Evidence).
How much Vitamin D should I take for 고혈압?
Studies have used various dosages. A commonly studied range is 600-800 IU/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin D?
Reported side effects may include Hypercalcemia at very high doses (fatigue, nausea, kidney stones), Constipation, Generally very safe at recommended doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin D and 고혈압?
We rate the evidence as Grade C (Some Evidence). This rating is based on 20 peer-reviewed studies with 30,000 total participants. The overall direction of effect is mixed.

Vitamin D 다른 건강 상태에 대한 근거

심부전 C

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