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Quercetin 관련 고혈압

B 근거 적어도 하나의 무작위 시험이 이를 지지하며, 대체로 일관된 결과를 보입니다.

Meta-analysis of 17 RCTs: systolic -3.09 mmHg at >=500 mg/day. More effective in >=8-week studies and hypertensive subjects. Phytosome form preferred for bioavailability.

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결론

Meta-analysis of 17 RCTs: systolic -3.09 mmHg at >=500 mg/day. More effective in >=8-week studies and hypertensive subjects. Phytosome form preferred for bioavailability.

Key Study Findings

In Vitro
Kyoh® Rocket Leaf Extract Regulates Proliferation and VEGF and FGF7 Expression in Human Dermal Follicle …
Dose: None vs: Untreated dermal follicle papilla cells Outcome: VEGF and FGF7 gene expression 효과: VEGF +267.3%, FGF7 +244.3% at 24h None

대상 집단: Human dermal follicle papilla cells (in vitro)

Review
Effects of plant-derived dietary antioxidants on Alzheimer's disease: Focus on ferroptosis.
Dose: None vs: None Outcome: Cognitive decline via ferroptosis regulation in AD 효과: None None

대상 집단: AD patients and healthy elderly

Review
Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications.
Dose: None vs: None Outcome: None 효과: None None

대상 집단: review of plant-derived anti-inflammatory compounds for chronic disease prevention

Other
Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating …
Dose: None vs: Allergic rhinitis mouse model vs control Outcome: Rhinitis symptoms and serum inflammatory indicators 효과: None None

대상 집단: Allergic rhinitis mouse model

Review
The Roles of Flavonoids and Other Plant-Based Phenolics in Mitigating Diabetes-Induced Macrovascular Complications.
Dose: None vs: None Outcome: None 효과: None None

대상 집단: Review of flavonoids/phenolics in diabetic macrovascular

Key Statistics

17

연구

900

참여자

Positive

B

등급

Referenced Papers

Voprosy pitaniia 2023 19 인용
International journal of … 2022 23 인용
Biomedicine & pharmacotherapy … 2020 427 인용
Oxidative medicine and … 2017 87 인용
International journal of … 2006 92 인용
Current drug targets 2006 92 인용
Alternative medicine review … 2000

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

일반적으로 사용되는 용량

general:
500-1,000 mg/day
bloodpressuresupport:
500-730 mg/day

상한량: Not formally established; up to 1,000 mg/day used in clinical trials

연구에서 사용된 용량

용량 기간 효과 N
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --
None -- Positive --
None -- Mixed --
None -- Positive --
None -- Positive --

권장 복용 시간: With meals; vitamin C co-supplementation may enhance bioavailability

Safety & Side Effects

보고된 부작용

  • Generally well-tolerated
  • Headache (rare)
  • Mild gastrointestinal discomfort
  • Tingling in extremities (rare, high doses)

알려진 상호작용

  • Antibiotics (quinolones — may reduce efficacy)
  • Cyclosporine (may increase blood levels)
  • Anticoagulants (may have mild antiplatelet effect)
  • Blood pressure medications (additive effect)

일일 최대 섭취 허용량: Not formally established; up to 1,000 mg/day used in clinical trials

건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.

Frequently Asked Questions

Does Quercetin help with 고혈압?
Based on 17 studies with 900 participants, there is moderate evidence from clinical studies that Quercetin may support 고혈압 management. Our evidence grade is B (Good Evidence).
How much Quercetin should I take for 고혈압?
Studies have used various dosages. A commonly studied range is 500-1,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Quercetin?
Reported side effects may include Generally well-tolerated, Headache (rare), Mild gastrointestinal discomfort, Tingling in extremities (rare, high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Quercetin and 고혈압?
We rate the evidence as Grade B (Good Evidence). This rating is based on 17 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.

References

  1. [1] Kazuhiko Nakadate et al.. Int J Mol Sci. 2025. Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications. doi:10.3390/ijms26115206 PubMed
  2. [2] Monika Martiniakova et al.. Nutrients. 2025. Protective Role of Dietary Polyphenols in the Management and Treatment of Type 2 Diabetes Mellitus. doi:10.3390/nu17020275 PubMed
  3. [3] Matteo Naso et al.. Nutrients. 2025. Quercetin and Its Lecithin-Based Formulation: Potential Applications for Allergic Diseases Based on a Narrative Review. doi:10.3390/nu17091476 PubMed
  4. [4] Xing-Yuan Li et al.. J Ethnopharmacol. 2025. Inhibition of mitochondrial oxidative stress and apoptosis in the protection of Ginkgo biloba extract 50 against cognitive impairment. doi:10.1016/j.jep.2025.120059 PubMed
  5. [5] Ki-Yeon Yoo et al.. Biology (Basel). 2025. Therapeutic Potential of Natural Compounds for Brain Ischemia-Reperfusion Injury. doi:10.3390/biology14091153 PubMed
  6. [6] Sihong Huang et al.. Curr Comput Aided Drug Des. 2025. Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating Allergic Rhinitis Mouse Model based … doi:10.2174/0115734099299714240516160158 PubMed
  7. [7] Feng Gu et al.. Asia Pac J Clin Nutr. 2025. Effects of plant-derived dietary antioxidants on Alzheimer's disease: Focus on ferroptosis. doi:10.6133/apjcn.202512_34(6).0007 PubMed
  8. [8] Aminu Mohammed et al.. Phytother Res. 2025. The Roles of Flavonoids and Other Plant-Based Phenolics in Mitigating Diabetes-Induced Macrovascular Complications. doi:10.1002/ptr.70070 PubMed
  9. [9] Adal Mena-García et al.. Molecules. 2025. Kyoh® Rocket Leaf Extract Regulates Proliferation and VEGF and FGF7 Expression in Human Dermal Follicle Papilla Cells. doi:10.3390/molecules30071489 PubMed
  10. [10] Masoumeh Shamsi et al.. Iran J Pharm Res. 2024. Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes (SOD1, GPx, HO-1) by Quercetin … doi:10.5812/ijpr-151428 PubMed
  11. [11] Devi Datt Joshi et al.. Indian J Microbiol. 2024. Relevance of Indian Traditional Herbal Brews for Gut Microbiota Balance. doi:10.1007/s12088-024-01251-4 PubMed
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  13. [13] Sina Kaag et al.. Cells. 2023. Effects of Dietary Components on Mast Cells: Possible Use as Nutraceuticals for Allergies? doi:10.3390/cells12222602 PubMed
  14. [14] Karen S Coutinho-Wolino et al.. Nutr Res. 2022. Bioactive compounds modulating Toll-like 4 receptor (TLR4)-mediated inflammation: pathways involved and future perspectives. doi:10.1016/j.nutres.2022.09.001 PubMed
  15. [15] Alzbeta Katonova et al.. Int J Mol Sci. 2022. Effect of a Vegan Diet on Alzheimer's Disease. doi:10.3390/ijms232314924 PubMed
  16. [16] Minye Qu et al.. Evid Based Complement Alternat Med. 2022. Network Pharmacology and Molecular Docking Study of Yupingfeng Powder in the Treatment of Allergic Diseases. doi:10.1155/2022/1323744 PubMed
  17. [17] Pamela Senesi et al.. Int J Mol Sci. 2021. Diabetes Mellitus and Cardiovascular Diseases: Nutraceutical Interventions Related to Caloric Restriction. doi:10.3390/ijms22157772 PubMed
  18. [18] Takayuki Okumo et al.. Medicines (Basel). 2021. Inhibition of Angiogenic Factor Productions by Quercetin In Vitro and In Vivo. doi:10.3390/medicines8050022 PubMed
  19. [19] Gang Gong et al.. Biomed Pharmacother. 2020. Isorhamnetin: A review of pharmacological effects. doi:10.1016/j.biopha.2020.110301 PubMed
  20. [20] Wang Anlu et al.. Pharmacol Res. 2019. Using herbal medicine to target the "microbiota-metabolism-immunity" axis as possible therapy for cardiovascular disease. doi:10.1016/j.phrs.2019.02.018 PubMed
  21. [21] A Tressera-Rimbau et al.. Oxid Med Cell Longev. 2017. Dietary Polyphenols in the Prevention of Stroke. doi:10.1155/2017/7467962 PubMed
  22. [22] Kevin M Nash et al.. Integr Med Insights. 2015. Current Perspectives on the Beneficial Role of Ginkgo biloba in Neurological and Cerebrovascular Disorders. doi:10.4137/IMI.S25054 PubMed
  23. [23] Irfan Rahman. Int J Chron Obstruct Pulmon Dis. 2006. Antioxidant therapies in COPD. doi:10.2147/copd.2006.1.1.15 PubMed
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FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.