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Resveratrol
Resveratrol

antioxidant

다른 이름: trans-Resveratrol, 3,5,4'-Trihydroxystilbene, Red Wine Polyphenol

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About





            

                
Resveratrol is a polyphenolic stilbene that activates SIRT1 and AMPK pathways, enhances endothelial nitric oxide production, and inhibits LDL oxidation. A 2015 meta-analysis of 10 RCTs found resveratrol at >=150 mg/day reduced systolic blood pressure by 11.9 mmHg in hypertensive patients. Bioavailability remains a challenge due to rapid hepatic metabolism.

            

        

        

        
        
        

            

  
How It Works





            

                
Activates SIRT1 and AMPK pathways enhancing mitochondrial biogenesis; potent inhibitor of LDL oxidation and foam cell formation; enhances endothelial nitric oxide synthase (eNOS) expression improving vasodilation; inhibits platelet aggregation through COX-1 and thromboxane A2 pathways; anti-inflammatory via NF-kB suppression.

            

        

        

        
        
        

            

  
Evidence For Conditions





            

                

                    

                        
                            

                                건강 상태
                                등급
                                연구
                                참여자
                                
                            

                        
                        
                            
                            

                                
                                    
                                        High Blood Pressure (Hypertension)
                                    
                                
                                
                                    B

                                
                                
                                    10
                                
                                
                                    600
                                
                                
                                    
                                        보기 →
                                    
                                
                            

                            
                            

                                
                                    
                                        Atherosclerosis
                                    
                                
                                
                                    C

                                
                                
                                    5
                                
                                
                                    400
                                
                                
                                    
                                        보기 →
                                    
                                
                            

                            
                        
                    

                

            

        

        

        
        
        

            

  
Side Effects





            
    
                
                
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                    Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
                
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                    Headache
                
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                    May have estrogenic activity at high doses
                
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Drug & Supplement Interactions





            
    
                
                
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                    Anticoagulants (may inhibit platelet aggregation)
                
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                    CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
                
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                    Blood pressure medications (additive hypotensive effect)
                
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                    Estrogen-sensitive conditions (weak estrogenic activity)
                
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                복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.
            

        

        

        
        
        

            

  
Related Ingredients





            

                
                
                    Grape Seed Extract
                    
                
                
                
                    Astaxanthin
                    
                
                
                
                    Quercetin
                    
                
                
                
                    Lycopene
                    
                
                
            

        

        
    


    
    












    

        FDA 면책 조항:
        이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.