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Resveratrol cho High Blood Pressure (Hypertension)

B Bằng chứng Ít nhất một thử nghiệm ngẫu nhiên ủng hộ điều này, với các kết quả phần lớn nhất quán.

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

B

Kết luận

Meta-analysis: systolic -11.9 mmHg in hypertensives at >=150 mg/day. Improved flow-mediated dilation in multiple RCTs. Bioavailability limitations noted.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily so với: Placebo Outcome: Preeclampsia risk reduction Hiệu quả: ~50% risk reduction

Đối tượng nghiên cứu: Pregnant women with low calcium intake

Randomized Controlled Trial n=129 14 weeks
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women.
Dose: 75 mg so với: Placebo P < 0.001

Đối tượng nghiên cứu: Older adults at risk of cognitive decline

Key Statistics

10

Nghiên cứu

600

Người tham gia

↑

Positive

B

Xếp hạng

Referenced Papers

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues. Review
ESC heart failure 2025 58 trích dẫn
Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk. Review
Nutrients 2025 32 trích dẫn
Dietary supplements and prevention of preeclampsia. Review
Hypertension research : … 2025 10 trích dẫn
The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review. Other
Cardiovascular & hematological … 2025
Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway. Other
Acta biochimica Polonica 2022 10 trích dẫn
The Role of Resveratrol Administration in Human Obesity. Review
International journal of … 2021 50 trích dẫn
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women. Other
Nutrients 2020 49 trích dẫn
Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome. Other
Nutrients 2020 16 trích dẫn
Nutritional prevention of cognitive decline and dementia. Review
Acta bio-medica : … 2018 103 trích dẫn

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Liều lượng thường dùng

general:
150-500 mg/day
cardiovascularsupport:
250-500 mg/day trans-resveratrol

Giới hạn trên: Not formally established; GI discomfort common above 1,000 mg/day

Liều lượng đã nghiên cứu

Liều lượng Thời gian Hiệu quả N
500 mg daily -- Positive --
75 mg 14 weeks Positive 129

Thời điểm dùng tốt nhất: With meals; bioavailability enhanced by piperine co-supplementation

Safety & Side Effects

Tác dụng phụ đã được báo cáo

  • ⚠ Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses
  • ⚠ Headache
  • ⚠ May have estrogenic activity at high doses

Tương tác đã biết

  • ● Anticoagulants (may inhibit platelet aggregation)
  • ● CYP450 substrates (may inhibit CYP1A2, CYP3A4, CYP2D6)
  • ● Blood pressure medications (additive hypotensive effect)
  • ● Estrogen-sensitive conditions (weak estrogenic activity)

Mức hấp thụ tối đa cho phép: Not formally established; GI discomfort common above 1,000 mg/day

Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.

Frequently Asked Questions

Does Resveratrol help with High Blood Pressure (Hypertension)?
Based on 10 studies with 600 participants, there is moderate evidence from clinical studies that Resveratrol may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Resveratrol should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 150-500 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Resveratrol?
Reported side effects may include Gastrointestinal discomfort (nausea, diarrhea, cramping) at high doses, Headache, May have estrogenic activity at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Resveratrol and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Resveratrol cho các tình trạng khác

Atherosclerosis C

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References

  
    
    
    
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      [1]
      Zhuyubing Fang et al..
      ESC Heart Fail.
      2025.
      Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.
      doi:10.1002/ehf2.14947
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Hygerta Berisha et al..
      Nutrients.
      2025.
      Nutrition and Lifestyle Interventions in Managing Dyslipidemia and Cardiometabolic Risk.
      doi:10.3390/nu17050776
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Takafumi Ushida et al..
      Hypertens Res.
      2025.
      Dietary supplements and prevention of preeclampsia.
      doi:10.1038/s41440-025-02144-9
      PubMed
    
    4. 
    
    
  4. 
      [4]
      Ali Amini et al..
      Cardiovasc Hematol Disord Drug Targets.
      2025.
      The Effects of Resveratrol on Menopausal Cardio-metabolic Changes: A Systematic Review.
      doi:10.2174/011871529X398468250910225946
      PubMed
    
    5. 
    
    
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      [5]
      Tao Jin et al..
      Acta Biochim Pol.
      2022.
      Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway.
      doi:10.18388/abp.2020_5982
      PubMed
    
    6. 
    
    
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      [6]
      Laura M Mongioì et al..
      Int J Mol Sci.
      2021.
      The Role of Resveratrol Administration in Human Obesity.
      doi:10.3390/ijms22094362
      PubMed
    
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      [7]
      Jay Jay Thaung Zaw et al..
      Nutrients.
      2020.
      Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women.
      doi:10.3390/nu12030828
      PubMed
    
    8. 
    
    
  8. 
      [8]
      Raúl Francisco Pastor et al..
      Nutrients.
      2020.
      Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome.
      doi:10.3390/nu12103149
      PubMed
    
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      Ligia J Dominguez et al..
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      doi:10.23750/abm.v89i2.7401
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