Quercetin cho High Blood Pressure (Hypertension)
B Bằng chứng Ít nhất một thử nghiệm ngẫu nhiên ủng hộ điều này, với các kết quả phần lớn nhất quán.Meta-analysis of 17 RCTs: systolic -3.09 mmHg at >=500 mg/day. More effective in >=8-week studies and hypertensive subjects. Phytosome form preferred for bioavailability.
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B
Kết luận
Meta-analysis of 17 RCTs: systolic -3.09 mmHg at >=500 mg/day. More effective in >=8-week studies and hypertensive subjects. Phytosome form preferred for bioavailability.
Key Study Findings
In Vitro
Kyoh® Rocket Leaf Extract Regulates Proliferation and VEGF and FGF7 Expression in Human Dermal Follicle …
Dose: None
so với: Untreated dermal follicle papilla cells
Outcome: VEGF and FGF7 gene expression
Hiệu quả: VEGF +267.3%, FGF7 +244.3% at 24h
None
Đối tượng nghiên cứu: Human dermal follicle papilla cells (in vitro)
Review
Quercetin and Its Lecithin-Based Formulation: Potential Applications for Allergic Diseases Based on a Narrative Review.
Dose: None
so với: None
Outcome: None
Hiệu quả: None
None
Đối tượng nghiên cứu: None
Review
Effects of plant-derived dietary antioxidants on Alzheimer's disease: Focus on ferroptosis.
Dose: None
so với: None
Outcome: Cognitive decline via ferroptosis regulation in AD
Hiệu quả: None
None
Đối tượng nghiên cứu: AD patients and healthy elderly
Review
Anti-Inflammatory Actions of Plant-Derived Compounds and Prevention of Chronic Diseases: From Molecular Mechanisms to Applications.
Dose: None
so với: None
Outcome: None
Hiệu quả: None
None
Đối tượng nghiên cứu: review of plant-derived anti-inflammatory compounds for chronic disease prevention
Other
Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating …
Dose: None
so với: Allergic rhinitis mouse model vs control
Outcome: Rhinitis symptoms and serum inflammatory indicators
Hiệu quả: None
None
Đối tượng nghiên cứu: Allergic rhinitis mouse model
Review
The Roles of Flavonoids and Other Plant-Based Phenolics in Mitigating Diabetes-Induced Macrovascular Complications.
Dose: None
so với: None
Outcome: None
Hiệu quả: None
None
Đối tượng nghiên cứu: Review of flavonoids/phenolics in diabetic macrovascular
Key Statistics
17
Nghiên cứu
900
Người tham gia
↑
Positive
B
Xếp hạng
Referenced Papers
International journal of …
2025
32 trích dẫn
Protective Role of Dietary Polyphenols in the Management and Treatment of Type 2 Diabetes Mellitus.
Review
Nutrients
2025
32 trích dẫn
Nutrients
2025
9 trích dẫn
Journal of ethnopharmacology
2025
5 trích dẫn
Biology
2025
3 trích dẫn
Current computer-aided drug …
2025
2 trích dẫn
Asia Pacific journal …
2025
1 trích dẫn
Phytotherapy research : …
2025
1 trích dẫn
Molecules (Basel, Switzerland)
2025
Iranian journal of …
2024
4 trích dẫn
Indian journal of …
2024
2 trích dẫn
Voprosy pitaniia
2023
19 trích dẫn
Cells
2023
13 trích dẫn
Nutrition research (New …
2022
75 trích dẫn
International journal of …
2022
23 trích dẫn
Evidence-based complementary and …
2022
7 trích dẫn
International journal of …
2021
20 trích dẫn
Medicines (Basel, Switzerland)
2021
16 trích dẫn
Biomedicine & pharmacotherapy …
2020
427 trích dẫn
Pharmacological research
2019
31 trích dẫn
Oxidative medicine and …
2017
87 trích dẫn
Integrative medicine insights
2015
100 trích dẫn
International journal of …
2006
92 trích dẫn
Current drug targets
2006
92 trích dẫn
Journal of medicinal …
2002
135 trích dẫn
Alternative medicine review …
2000
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Liều lượng thường dùng
- general:
- 500-1,000 mg/day
- bloodpressuresupport:
- 500-730 mg/day
Giới hạn trên: Not formally established; up to 1,000 mg/day used in clinical trials
Liều lượng đã nghiên cứu
| Liều lượng | Thời gian | Hiệu quả | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
Thời điểm dùng tốt nhất: With meals; vitamin C co-supplementation may enhance bioavailability
Safety & Side Effects
Tác dụng phụ đã được báo cáo
- ⚠ Generally well-tolerated
- ⚠ Headache (rare)
- ⚠ Mild gastrointestinal discomfort
- ⚠ Tingling in extremities (rare, high doses)
Tương tác đã biết
- ● Antibiotics (quinolones — may reduce efficacy)
- ● Cyclosporine (may increase blood levels)
- ● Anticoagulants (may have mild antiplatelet effect)
- ● Blood pressure medications (additive effect)
Mức hấp thụ tối đa cho phép: Not formally established; up to 1,000 mg/day used in clinical trials
Luôn tham khảo ý kiến bác sĩ trước khi bắt đầu sử dụng bất kỳ thực phẩm bổ sung nào.Luôn tham khảo ý kiến chuyên gia y tế trước khi sử dụng bất kỳ thực phẩm chức năng nào.
Frequently Asked Questions
Does Quercetin help with High Blood Pressure (Hypertension)?
Based on 17 studies with 900 participants, there is moderate evidence from clinical studies that Quercetin may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Quercetin should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 500-1,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Quercetin?
Reported side effects may include Generally well-tolerated, Headache (rare), Mild gastrointestinal discomfort, Tingling in extremities (rare, high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Quercetin and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 17 peer-reviewed studies with 900 total participants. The overall direction of effect is positive.
Related Evidence
Các thành phần khác cho High Blood Pressure (Hypertension)
Quercetin cho các tình trạng khác
References
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- [2] Monika Martiniakova et al.. Nutrients. 2025. Protective Role of Dietary Polyphenols in the Management and Treatment of Type 2 Diabetes Mellitus. doi:10.3390/nu17020275 PubMed
- [3] Matteo Naso et al.. Nutrients. 2025. Quercetin and Its Lecithin-Based Formulation: Potential Applications for Allergic Diseases Based on a Narrative Review. doi:10.3390/nu17091476 PubMed
- [4] Xing-Yuan Li et al.. J Ethnopharmacol. 2025. Inhibition of mitochondrial oxidative stress and apoptosis in the protection of Ginkgo biloba extract 50 against cognitive impairment. doi:10.1016/j.jep.2025.120059 PubMed
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- [7] Feng Gu et al.. Asia Pac J Clin Nutr. 2025. Effects of plant-derived dietary antioxidants on Alzheimer's disease: Focus on ferroptosis. doi:10.6133/apjcn.202512_34(6).0007 PubMed
- [8] Aminu Mohammed et al.. Phytother Res. 2025. The Roles of Flavonoids and Other Plant-Based Phenolics in Mitigating Diabetes-Induced Macrovascular Complications. doi:10.1002/ptr.70070 PubMed
- [9] Adal Mena-García et al.. Molecules. 2025. Kyoh® Rocket Leaf Extract Regulates Proliferation and VEGF and FGF7 Expression in Human Dermal Follicle Papilla Cells. doi:10.3390/molecules30071489 PubMed
- [10] Masoumeh Shamsi et al.. Iran J Pharm Res. 2024. Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes (SOD1, GPx, HO-1) by Quercetin … doi:10.5812/ijpr-151428 PubMed
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- [13] Sina Kaag et al.. Cells. 2023. Effects of Dietary Components on Mast Cells: Possible Use as Nutraceuticals for Allergies? doi:10.3390/cells12222602 PubMed
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- [17] Pamela Senesi et al.. Int J Mol Sci. 2021. Diabetes Mellitus and Cardiovascular Diseases: Nutraceutical Interventions Related to Caloric Restriction. doi:10.3390/ijms22157772 PubMed
- [18] Takayuki Okumo et al.. Medicines (Basel). 2021. Inhibition of Angiogenic Factor Productions by Quercetin In Vitro and In Vivo. doi:10.3390/medicines8050022 PubMed
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- [21] A Tressera-Rimbau et al.. Oxid Med Cell Longev. 2017. Dietary Polyphenols in the Prevention of Stroke. doi:10.1155/2017/7467962 PubMed
- [22] Kevin M Nash et al.. Integr Med Insights. 2015. Current Perspectives on the Beneficial Role of Ginkgo biloba in Neurological and Cerebrovascular Disorders. doi:10.4137/IMI.S25054 PubMed
- [23] Irfan Rahman. Int J Chron Obstruct Pulmon Dis. 2006. Antioxidant therapies in COPD. doi:10.2147/copd.2006.1.1.15 PubMed
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