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Selenium لـ Oxidative Stress (Cardiovascular)

B

KiSel-10 trial: 54% CV mortality reduction with combination selenium (200 mcg) + CoQ10 (200 mg) over 4 years. 12-year follow-up confirmed sustained benefit. Most relevant in selenium-deficient populations.

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B

الخلاصة

KiSel-10 trial: 54% CV mortality reduction with combination selenium (200 mcg) + CoQ10 (200 mg) over 4 years. 12-year follow-up confirmed sustained benefit. Most relevant in selenium-deficient populations.

Key Statistics

3

الدراسات

600

المشاركون

Positive

B

التقييم

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:
55 mcg/day
cardiovascularantioxidant:
100-200 mcg/day

الحد الأعلى: 400 mcg/day (risk of selenosis above this level)

أفضل وقت للتناول: With meals

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Selenosis at high doses (garlic breath odor, hair/nail loss, nausea)
  • GI discomfort at moderate-high doses
  • Potential increased type 2 diabetes risk at high supplemental doses

التفاعلات المعروفة

  • Cisplatin and other chemotherapy drugs (may affect efficacy)
  • Statins (may enhance antioxidant effects)
  • CoQ10 (synergistic cardiovascular benefit — KiSel-10 combination)

الحد الأقصى المسموح به: 400 mcg/day (risk of selenosis above this level)

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Selenium help with Oxidative Stress (Cardiovascular)?
Based on 3 studies with 600 participants, there is moderate evidence from clinical studies that Selenium may support Oxidative Stress (Cardiovascular) management. Our evidence grade is B (Good Evidence).
How much Selenium should I take for Oxidative Stress (Cardiovascular)?
Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Selenium?
Reported side effects may include Selenosis at high doses (garlic breath odor, hair/nail loss, nausea), GI discomfort at moderate-high doses, Potential increased type 2 diabetes risk at high supplemental doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Selenium and Oxidative Stress (Cardiovascular)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 3 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Related Evidence

مكونات أخرى لـ Oxidative Stress (Cardiovascular)

Selenium لحالات أخرى

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.