Selenium के लिए Oxidative Stress (Cardiovascular)
B संबंधित साक्ष्य कम से कम एक यादृच्छिक परीक्षण इसका समर्थन करता है, जिसके परिणाम अधिकतर सुसंगत हैं।KiSel-10 trial: 54% CV mortality reduction with combination selenium (200 mcg) + CoQ10 (200 mg) over 4 years. 12-year follow-up confirmed sustained benefit. Most relevant in selenium-deficient populations.
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B
निष्कर्ष
KiSel-10 trial: 54% CV mortality reduction with combination selenium (200 mcg) + CoQ10 (200 mg) over 4 years. 12-year follow-up confirmed sustained benefit. Most relevant in selenium-deficient populations.
Key Study Findings
animal study
Protective mechanisms of zinc and/or selenium supplementation against BPA-induced male and offspring reproductive toxicity: Insights …
Dose: zinc and/or selenium supplementation; doses not specified in abstract
बनाम: Placebo
प्रभाव: None
None
Review
Potential Applications and Risks of Supranutritional Selenium Supplementation in Metabolic Dysfunction-Associated Steatotic Liver Disease: A …
Dose: None
बनाम: None
Outcome: MASLD treatment and prevention
प्रभाव: None
None
जनसंख्या: Patients with metabolic steatotic liver disease (review)
Review
Mineral Homeostasis and Depression: Implications for Prevention and Therapeutic Support-A Narrative Review.
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: People with depression
preclinical animal study with human correlational observation
Maintaining myoprotein and redox homeostasis via an orally recharged nanoparticulate supplement potentiates sarcopenia treatment.
Dose: oral administration; specific dose not reported in abstract
बनाम: Placebo
प्रभाव: None
None
Review
The Role of Various Types of Diets in the Treatments of Depressive Disorders.
Dose: None
बनाम: None
Outcome: None
प्रभाव: None
None
जनसंख्या: Adults with depression
prospective controlled study
n=30
Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and …
Dose: None
बनाम: Placebo
प्रभाव: None
None
Key Statistics
3
अध्ययन
600
प्रतिभागी
↑
Positive
B
ग्रेड
Referenced Papers
Environment international
2026
Biomaterials
2025
8 उद्धरण
Nutrients
2025
3 उद्धरण
Cutaneous and ocular …
2025
1 उद्धरण
Medicina (Kaunas, Lithuania)
2025
1 उद्धरण
Biogerontology
2025
International journal of …
2025
Molecules (Basel, Switzerland)
2024
13 उद्धरण
Food & function
2024
6 उद्धरण
Journal of dairy …
2024
4 उद्धरण
Shining a Light on Selenium: a Meta-analysis of Supplementation in Multiple Sclerosis.
Meta-Analysis
Biological trace element …
2024
2 उद्धरण
Nutrients
2023
75 उद्धरण
International journal of …
2023
45 उद्धरण
BMC endocrine disorders
2023
25 उद्धरण
The Role of Dietary Antioxidants and Their Potential Mechanisms in Alzheimer's Disease Treatment.
Review
Metabolites
2023
13 उद्धरण
Journal of animal …
2023
11 उद्धरण
Animals : an …
2023
7 उद्धरण
Memory Recovery Effect of a New Bioactive Innovative Combination in Rats with Experimental Dementia.
Other
Antioxidants (Basel, Switzerland)
2023
5 उद्धरण
Antioxidants (Basel, Switzerland)
2022
13 उद्धरण
Animal bioscience
2022
9 उद्धरण
Journal of inflammation …
2021
34 उद्धरण
Biological trace element …
2021
18 उद्धरण
Nutricion hospitalaria
2021
10 उद्धरण
Redox biology
2020
184 उद्धरण
Environmental science and …
2020
79 उद्धरण
Molecules (Basel, Switzerland)
2019
472 उद्धरण
British journal of …
2019
14 उद्धरण
Advances in clinical …
2018
200 उद्धरण
Nutricion hospitalaria
2018
32 उद्धरण
JAMA neurology
2017
258 उद्धरण
Multiple micronutrient supplementation and birth outcomes: The potential importance of selenium.
Review
Placenta
2016
23 उद्धरण
Biological trace element …
2015
1 उद्धरण
Free radical biology …
2013
208 उद्धरण
Molecular nutrition & …
2012
65 उद्धरण
Biological trace element …
2012
31 उद्धरण
Alcoholism, clinical and …
2012
19 उद्धरण
Journal of clinical …
2011
396 उद्धरण
Nutrition and cancer
2011
19 उद्धरण
Nutrition in clinical …
2008
125 उद्धरण
The American journal …
2000
472 उद्धरण
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
सामान्य रूप से उपयोग की जाने वाली खुराकें
- general:
- 55 mcg/day
- cardiovascularantioxidant:
- 100-200 mcg/day
अधिकतम सीमा: 400 mcg/day (risk of selenosis above this level)
अनुसंधान में अध्ययन की गई खुराकें
| खुराक | अवधि | प्रभाव | N |
|---|---|---|---|
| zinc and/or selenium supplementation; doses not specified in abstract | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| oral administration; specific dose not reported in abstract | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | 30 |
| None | -- | Negative | 2065 |
| None | -- | Positive | -- |
सेवन का सर्वोत्तम समय: With meals
Safety & Side Effects
रिपोर्ट किए गए दुष्प्रभाव
- ⚠ Selenosis at high doses (garlic breath odor, hair/nail loss, nausea)
- ⚠ GI discomfort at moderate-high doses
- ⚠ Potential increased type 2 diabetes risk at high supplemental doses
ज्ञात अंतःक्रियाएँ
- ● Cisplatin and other chemotherapy drugs (may affect efficacy)
- ● Statins (may enhance antioxidant effects)
- ● CoQ10 (synergistic cardiovascular benefit — KiSel-10 combination)
सहनीय अधिकतम सेवन: 400 mcg/day (risk of selenosis above this level)
कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।
Frequently Asked Questions
Does Selenium help with Oxidative Stress (Cardiovascular)?
Based on 3 studies with 600 participants, there is moderate evidence from clinical studies that Selenium may support Oxidative Stress (Cardiovascular) management. Our evidence grade is B (Good Evidence).
How much Selenium should I take for Oxidative Stress (Cardiovascular)?
Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Selenium?
Reported side effects may include Selenosis at high doses (garlic breath odor, hair/nail loss, nausea), GI discomfort at moderate-high doses, Potential increased type 2 diabetes risk at high supplemental doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Selenium and Oxidative Stress (Cardiovascular)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 3 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.
Related Evidence
इसके लिए अन्य सामग्री Oxidative Stress (Cardiovascular)
Selenium अन्य स्वास्थ्य स्थितियों के लिए
References
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FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।