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Selenium für Oxidative Stress (Cardiovascular)

B

KiSel-10 trial: 54% CV mortality reduction with combination selenium (200 mcg) + CoQ10 (200 mg) over 4 years. 12-year follow-up confirmed sustained benefit. Most relevant in selenium-deficient populations.

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KiSel-10 trial: 54% CV mortality reduction with combination selenium (200 mcg) + CoQ10 (200 mg) over 4 years. 12-year follow-up confirmed sustained benefit. Most relevant in selenium-deficient populations.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
3

        
Studien

    

    

        
600

        
Teilnehmer

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Bewertung

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Übliche Dosierungen

                

                    
                    

                        
general:

                        
55 mcg/day

                    

                    
                    

                        
cardiovascularantioxidant:

                        
100-200 mcg/day

                    

                    
                

                
                

                    Obergrenze: 400 mcg/day (risk of selenosis above this level)
                

                
            

            

            

            
            

                Beste Einnahmezeit: With meals
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Gemeldete Nebenwirkungen

                    
    
                        
                        
  • 
                            ⚠
                            Selenosis at high doses (garlic breath odor, hair/nail loss, nausea)
                        
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                            ⚠
                            GI discomfort at moderate-high doses
                        
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                            ⚠
                            Potential increased type 2 diabetes risk at high supplemental doses
                        
    • 
                        
                    

                

                

                
                

                    
Bekannte Wechselwirkungen

                    
    
                        
                        
  • 
                            ●
                            Cisplatin and other chemotherapy drugs (may affect efficacy)
                        
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  • 
                            ●
                            Statins (may enhance antioxidant effects)
                        
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  • 
                            ●
                            CoQ10 (synergistic cardiovascular benefit — KiSel-10 combination)
                        
    • 
                        
                    

                

                

                
                

                    

                        Tolerierbare Höchstaufnahmemenge: 400 mcg/day (risk of selenosis above this level)
                    

                

                
            

            

                Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Selenium help with Oxidative Stress (Cardiovascular)?
            
        
        

            Based on 3 studies with 600 participants, there is moderate evidence from clinical studies that Selenium may support Oxidative Stress (Cardiovascular) management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Selenium should I take for Oxidative Stress (Cardiovascular)?
            
        
        

            Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Selenium?
            
        
        

            Reported side effects may include Selenosis at high doses (garlic breath odor, hair/nail loss, nausea), GI discomfort at moderate-high doses, Potential increased type 2 diabetes risk at high supplemental doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Selenium and Oxidative Stress (Cardiovascular)?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 3 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
Andere Inhaltsstoffe für Oxidative Stress (Cardiovascular)

                    

                        
                        
                            PQQ (Pyrroloquinoline Quinone)
                            C

                        
                        
                    

                

                

                
                

                    
Selenium für andere Beschwerden

                    

                        
                        
                            Coronary Artery Disease (CAD)
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

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        Diese Aussagen wurden nicht von der Food and Drug Administration bewertet. Die Produkte und Informationen auf dieser Website sind nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Die dargestellten Evidenzbewertungen basieren auf unserer Analyse veröffentlichter begutachteter Forschung und stellen keine medizinische Beratung dar. Konsultieren Sie immer Ihren Arzt, bevor Sie mit der Einnahme von Nahrungsergänzungsmitteln beginnen.