Selenium 관련 산화 스트레스(심혈관)
B 근거 적어도 하나의 무작위 시험이 이를 지지하며, 대체로 일관된 결과를 보입니다.KiSel-10 trial: 54% CV mortality reduction with combination selenium (200 mcg) + CoQ10 (200 mg) over 4 years. 12-year follow-up confirmed sustained benefit. Most relevant in selenium-deficient populations.
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B
결론
KiSel-10 trial: 54% CV mortality reduction with combination selenium (200 mcg) + CoQ10 (200 mg) over 4 years. 12-year follow-up confirmed sustained benefit. Most relevant in selenium-deficient populations.
Key Study Findings
animal study
Protective mechanisms of zinc and/or selenium supplementation against BPA-induced male and offspring reproductive toxicity: Insights …
Dose: zinc and/or selenium supplementation; doses not specified in abstract
vs: Placebo
효과: None
None
Review
Potential Applications and Risks of Supranutritional Selenium Supplementation in Metabolic Dysfunction-Associated Steatotic Liver Disease: A …
Dose: None
vs: None
Outcome: MASLD treatment and prevention
효과: None
None
대상 집단: Patients with metabolic steatotic liver disease (review)
Review
Mineral Homeostasis and Depression: Implications for Prevention and Therapeutic Support-A Narrative Review.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: People with depression
preclinical animal study with human correlational observation
Maintaining myoprotein and redox homeostasis via an orally recharged nanoparticulate supplement potentiates sarcopenia treatment.
Dose: oral administration; specific dose not reported in abstract
vs: Placebo
효과: None
None
Review
The Role of Various Types of Diets in the Treatments of Depressive Disorders.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Adults with depression
prospective controlled study
n=30
Investigation of ischaemia-modified albumin and antioxidant vitamins and minerals levels in alopecia areata patients and …
Dose: None
vs: Placebo
효과: None
None
Key Statistics
3
연구
600
참여자
↑
Positive
B
등급
Referenced Papers
Environment international
2026
Biomaterials
2025
8 인용
Nutrients
2025
3 인용
Cutaneous and ocular …
2025
1 인용
Medicina (Kaunas, Lithuania)
2025
1 인용
Biogerontology
2025
International journal of …
2025
Molecules (Basel, Switzerland)
2024
13 인용
Food & function
2024
6 인용
Journal of dairy …
2024
4 인용
Shining a Light on Selenium: a Meta-analysis of Supplementation in Multiple Sclerosis.
Meta-Analysis
Biological trace element …
2024
2 인용
Nutrients
2023
75 인용
International journal of …
2023
45 인용
BMC endocrine disorders
2023
25 인용
The Role of Dietary Antioxidants and Their Potential Mechanisms in Alzheimer's Disease Treatment.
Review
Metabolites
2023
13 인용
Journal of animal …
2023
11 인용
Animals : an …
2023
7 인용
Memory Recovery Effect of a New Bioactive Innovative Combination in Rats with Experimental Dementia.
Other
Antioxidants (Basel, Switzerland)
2023
5 인용
Antioxidants (Basel, Switzerland)
2022
13 인용
Animal bioscience
2022
9 인용
Journal of inflammation …
2021
34 인용
Biological trace element …
2021
18 인용
Nutricion hospitalaria
2021
10 인용
Redox biology
2020
184 인용
Environmental science and …
2020
79 인용
Molecules (Basel, Switzerland)
2019
472 인용
British journal of …
2019
14 인용
Advances in clinical …
2018
200 인용
Nutricion hospitalaria
2018
32 인용
JAMA neurology
2017
258 인용
Multiple micronutrient supplementation and birth outcomes: The potential importance of selenium.
Review
Placenta
2016
23 인용
Biological trace element …
2015
1 인용
Free radical biology …
2013
208 인용
Molecular nutrition & …
2012
65 인용
Biological trace element …
2012
31 인용
Alcoholism, clinical and …
2012
19 인용
Journal of clinical …
2011
396 인용
Nutrition and cancer
2011
19 인용
Nutrition in clinical …
2008
125 인용
The American journal …
2000
472 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 55 mcg/day
- cardiovascularantioxidant:
- 100-200 mcg/day
상한량: 400 mcg/day (risk of selenosis above this level)
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| zinc and/or selenium supplementation; doses not specified in abstract | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| oral administration; specific dose not reported in abstract | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | 30 |
| None | -- | Negative | 2065 |
| None | -- | Positive | -- |
권장 복용 시간: With meals
Safety & Side Effects
보고된 부작용
- ⚠ Selenosis at high doses (garlic breath odor, hair/nail loss, nausea)
- ⚠ GI discomfort at moderate-high doses
- ⚠ Potential increased type 2 diabetes risk at high supplemental doses
알려진 상호작용
- ● Cisplatin and other chemotherapy drugs (may affect efficacy)
- ● Statins (may enhance antioxidant effects)
- ● CoQ10 (synergistic cardiovascular benefit — KiSel-10 combination)
일일 최대 섭취 허용량: 400 mcg/day (risk of selenosis above this level)
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Selenium help with 산화 스트레스(심혈관)?
Based on 3 studies with 600 participants, there is moderate evidence from clinical studies that Selenium may support 산화 스트레스(심혈관) management. Our evidence grade is B (Good Evidence).
How much Selenium should I take for 산화 스트레스(심혈관)?
Studies have used various dosages. A commonly studied range is 55 mcg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Selenium?
Reported side effects may include Selenosis at high doses (garlic breath odor, hair/nail loss, nausea), GI discomfort at moderate-high doses, Potential increased type 2 diabetes risk at high supplemental doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Selenium and 산화 스트레스(심혈관)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 3 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 산화 스트레스(심혈관)
Selenium 다른 건강 상태에 대한 근거
References
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