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Magnesium لـ High Blood Pressure (Hypertension)

B الأدلة تدعم ذلك تجربة عشوائية واحدة على الأقل، مع نتائج متسقة في معظمها.

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

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الخلاصة

Meta-analysis of 34 RCTs: systolic -2.0 mmHg, diastolic -1.78 mmHg at 368 mg/day. Greater effects in magnesium-deficient populations. Approximately 50% of US adults consume below the estimated average requirement.

Key Study Findings

Review
Dietary supplements and prevention of preeclampsia.
Dose: 500 mg daily مقابل: Placebo Outcome: Preeclampsia risk reduction التأثير: ~50% risk reduction None

المجتمع المدروس: Pregnant women with low calcium intake

Case Reports 13.0 weeks
A case report of Gitelman syndrome in children.
Dose: 3 g مقابل: None Outcome: pain reduction التأثير: None None

المجتمع المدروس: Hypokalemia

Review
Nutritional prevention of cognitive decline and dementia.
Dose: None مقابل: None Outcome: Cognitive decline prevention التأثير: None None

المجتمع المدروس: Older adults at risk of cognitive decline

Systematic Review
The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on …
Dose: varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements مقابل: Placebo التأثير: None None
Review
Prevention of hypokalemia caused by diuretics.
Dose: None مقابل: None Outcome: mineral status التأثير: None None

المجتمع المدروس: hypertensive patients

Randomized Controlled Trial n=48 26.0 weeks
Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for …
Dose: 100 mg/d مقابل: control group Outcome: blood pressure التأثير: None None

المجتمع المدروس: hypertensive patients

Key Statistics

34

الدراسات

2028

المشاركون

Positive

B

التقييم

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:
310-420 mg/day
bloodpressuresupport:
300-500 mg/day
cardiovascularsupport:
300-400 mg/day elemental magnesium

الحد الأعلى: 350 mg/day from supplements only (no UL for food magnesium)

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
500 mg daily -- Positive --
3 g 13.0 weeks Mixed --
None -- Mixed --
varied: EFAs, B vitamins, vitamin C, magnesium, zinc as dietary supplements -- Mixed --
None -- Mixed --
100 mg/d 26.0 weeks Mixed 48

أفضل وقت للتناول: With meals to reduce GI side effects; evening dosing may support sleep

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Diarrhea (especially magnesium oxide and citrate)
  • Nausea
  • Abdominal cramping
  • Excessive doses may cause hypotension or cardiac depression

التفاعلات المعروفة

  • Bisphosphonates (reduced absorption — separate by 2 hours)
  • Antibiotics (tetracyclines, fluoroquinolones — separate by 2-4 hours)
  • Diuretics (thiazides reduce, loop diuretics increase magnesium loss)
  • Proton pump inhibitors (long-term use may cause hypomagnesemia)

الحد الأقصى المسموح به: 350 mg/day from supplements only (no UL for food magnesium)

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Magnesium help with High Blood Pressure (Hypertension)?
Based on 34 studies with 2,028 participants, there is moderate evidence from clinical studies that Magnesium may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
How much Magnesium should I take for High Blood Pressure (Hypertension)?
Studies have used various dosages. A commonly studied range is 310-420 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Magnesium?
Reported side effects may include Diarrhea (especially magnesium oxide and citrate), Nausea, Abdominal cramping, Excessive doses may cause hypotension or cardiac depression. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Magnesium and High Blood Pressure (Hypertension)?
We rate the evidence as Grade B (Good Evidence). This rating is based on 34 peer-reviewed studies with 2,028 total participants. The overall direction of effect is positive.

References

  1. [1] Takafumi Ushida et al.. Hypertens Res. 2025. Dietary supplements and prevention of preeclampsia. doi:10.1038/s41440-025-02144-9 PubMed
  2. [2] Jing Ying et al.. Medicine (Baltimore). 2023. A case report of Gitelman syndrome in children. doi:10.1097/MD.0000000000033509 PubMed
  3. [3] Ligia J Dominguez et al.. Acta Biomed. 2018. Nutritional prevention of cognitive decline and dementia. doi:10.23750/abm.v89i2.7401 PubMed
  4. [4] Delia McCabe et al.. JBI Database System Rev Implement Rep. 2017. The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: a … doi:10.11124/JBISRIR-2016-002965 PubMed
  5. [5] E Bourke et al.. Heart Dis Stroke. 1994. Prevention of hypokalemia caused by diuretics. PubMed
  6. [6] T Dyckner et al.. Eur J Clin Pharmacol. 1986. Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive heart failure and/or arterial … doi:10.1007/BF00542411 PubMed

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.