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Quercetin 用于 动脉粥样硬化

D 研究 目前仅存在初步研究（实验室研究、病例报告）。

In vitro evidence for PCSK9 inhibition and reduced foam cell formation. Limited human data on atherosclerosis endpoints specifically.

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            D

        

        

            
结论

            
            
In vitro evidence for PCSK9 inhibition and reduced foam cell formation. Limited human data on atherosclerosis endpoints specifically.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Other
                
                
                
                
            

            
                Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating …
            
            

                
                Dose: None
                
                
                vs: Allergic rhinitis mouse model vs control
                
                
                Outcome: Rhinitis symptoms and serum inflammatory indicators
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: Allergic rhinitis mouse model

            
        

        
        

            

                
                    Other
                
                
                
                
            

            
                Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes …
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Inflammatory markers
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: None

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Using herbal medicine to target the "microbiota-metabolism-immunity" axis as possible therapy for cardiovascular disease.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Gut microbiota composition
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: None

            
        

        
        

            

                
                    In Vitro
                
                
                
                
            

            
                Dietary Polyphenols in the Prevention of Stroke.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Stroke prevention
                
                
                效果: None
                
                
                None
                
            

            
            
研究人群: General population (CVD risk)

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
2

        
研究数量

    

    

        
100

        
受试者

    

    

        
            
            ↑
            
        
        
Positive

    

    

        D

        
等级

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating Allergic Rhinitis Mouse Model based …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Current computer-aided drug …
                        2025
                        
                        2 次引用
                        
                    

                

                
                

                    

                        
                            Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes (SOD1, GPx, HO-1) by Quercetin …
                        
                        
                            
                                Other
                            
                            
                            
                        
                    

                    

                        Iranian journal of …
                        2024
                        
                        4 次引用
                        
                    

                

                
                

                    

                        
                            Using herbal medicine to target the "microbiota-metabolism-immunity" axis as possible therapy for cardiovascular disease.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Pharmacological research
                        2019
                        
                        31 次引用
                        
                    

                

                
                

                    

                        
                            Dietary Polyphenols in the Prevention of Stroke.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Oxidative medicine and …
                        2017
                        
                        87 次引用
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
常用剂量

                

                    
                    

                        
general:

                        
500-1,000 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
500-730 mg/day

                    

                    
                

                
                

                    上限： Not formally established; up to 1,000 mg/day used in clinical trials
                

                
            

            

            
            

                
研究中使用的剂量

                

                    

                        
                            

                                剂量
                                持续时间
                                效果
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Mixed
                                    
                                
                                --
                            

                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                最佳服用时间： With meals; vitamin C co-supplementation may enhance bioavailability
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
已报告的副作用

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Tingling in extremities (rare, high doses)
                        
    • 
                        
                    

                

                

                
                

                    
已知相互作用

                    
    
                        
                        
  • 
                            ●
                            Antibiotics (quinolones — may reduce efficacy)
                        
    • 
                        
                        
  • 
                            ●
                            Cyclosporine (may increase blood levels)
                        
    • 
                        
                        
  • 
                            ●
                            Anticoagulants (may have mild antiplatelet effect)
                        
    • 
                        
                        
  • 
                            ●
                            Blood pressure medications (additive effect)
                        
    • 
                        
                    

                

                

                
                

                    

                        可耐受最高摄入量： Not formally established; up to 1,000 mg/day used in clinical trials
                    

                

                
            

            

                在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Quercetin help with 动脉粥样硬化?
            
        
        

            Based on 2 studies with 100 participants, there is preliminary evidence that needs more research that Quercetin may support 动脉粥样硬化 management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Quercetin should I take for 动脉粥样硬化?
            
        
        

            Studies have used various dosages. A commonly studied range is 500-1,000 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Quercetin?
            
        
        

            Reported side effects may include Generally well-tolerated, Headache (rare), Mild gastrointestinal discomfort, Tingling in extremities (rare, high doses). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Quercetin and 动脉粥样硬化?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 2 peer-reviewed studies with 100 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                
                

                
                

                    
Quercetin 用于其他健康状况

                    

                        
                        
                            高血压
                            B

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      Sihong Huang et al..
      Curr Comput Aided Drug Des.
      2025.
      Exploration of Potential Targets and Molecular Mechanisms of the Yiqi Jianpi Tongqiao Formula in Treating Allergic Rhinitis Mouse Model based …
      doi:10.2174/0115734099299714240516160158
      PubMed
    
    2. 
    
    
  2. 
      [2]
      Masoumeh Shamsi et al..
      Iran J Pharm Res.
      2024.
      Dual Modulation of Canonical and Non-canonical TGF-β/ROS/Erk1/2 Pathways: Synergistic Activation of Nrf-2 and Antioxidant Enzymes (SOD1, GPx, HO-1) by Quercetin …
      doi:10.5812/ijpr-151428
      PubMed
    
    3. 
    
    
  3. 
      [3]
      Wang Anlu et al..
      Pharmacol Res.
      2019.
      Using herbal medicine to target the "microbiota-metabolism-immunity" axis as possible therapy for cardiovascular disease.
      doi:10.1016/j.phrs.2019.02.018
      PubMed
    
    4. 
    
    
  4. 
      [4]
      A Tressera-Rimbau et al..
      Oxid Med Cell Longev.
      2017.
      Dietary Polyphenols in the Prevention of Stroke.
      doi:10.1155/2017/7467962
      PubMed
    
    5. 
    
  















    

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