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Garlic ： High Blood Pressure (Hypertension)

A

Meta-analysis of 12 RCTs: systolic -8.3 mmHg, diastolic -5.5 mmHg in hypertensives. Effect may be comparable to first-line antihypertensives. AGE at Heart trial showed 80% reduction in coronary calcium progression.

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            A

        

        

            
結論

            
            
Meta-analysis of 12 RCTs: systolic -8.3 mmHg, diastolic -5.5 mmHg in hypertensives. Effect may be comparable to first-line antihypertensives. AGE at Heart trial showed 80% reduction in coronary calcium progression.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
12

        
研究数

    

    

        
550

        
参加者数

    

    

        
            
            ↑
            
        
        
Positive

    

    

        A

        
グレード

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
一般的な使用量

                

                    
                    

                        
freshgarlic:

                        
2-5g/day (1-2 cloves)

                    

                    
                    

                        
agedgarlicextract:

                        
600-1,200 mg/day

                    

                    
                    

                        
allicinstandardized:

                        
300-600 mg/day (5-12 mg allicin)

                    

                    
                

                
                

                    上限量： Not formally established; GI discomfort and body odor limit high doses
                

                
            

            

            

            
            

                推奨摂取タイミング： With meals to reduce GI side effects; enteric-coated tablets for allicin delivery
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
報告されている副作用

                    
    
                        
                        
  • 
                            ⚠
                            Body odor and bad breath (less with AGE)
                        
    • 
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort (heartburn, nausea, gas)
                        
    • 
                        
                        
  • 
                            ⚠
                            Increased bleeding risk
                        
    • 
                        
                        
  • 
                            ⚠
                            Allergic reactions (rare)
                        
    • 
                        
                    

                

                

                
                

                    
既知の相互作用

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (increased bleeding risk — discontinue 7 days before surgery)
                        
    • 
                        
                        
  • 
                            ●
                            Antiplatelet drugs (additive antiplatelet effect)
                        
    • 
                        
                        
  • 
                            ●
                            HIV protease inhibitors (saquinavir — reduced levels)
                        
    • 
                        
                        
  • 
                            ●
                            CYP3A4 substrates (may alter metabolism)
                        
    • 
                        
                        
  • 
                            ●
                            Blood pressure medications (additive hypotensive effect)
                        
    • 
                        
                    

                

                

                
                

                    

                        耐容上限摂取量： Not formally established; GI discomfort and body odor limit high doses
                    

                

                
            

            

                サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Garlic help with High Blood Pressure (Hypertension)?
            
        
        

            Based on 12 studies with 550 participants, there is strong evidence from multiple clinical trials that Garlic may support High Blood Pressure (Hypertension) management. Our evidence grade is A (Strong Evidence).
        

    

    
    

        
            How much Garlic should I take for High Blood Pressure (Hypertension)?
            
        
        

            Studies have used various dosages. A commonly studied range is 2-5g/day (1-2 cloves). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Garlic?
            
        
        

            Reported side effects may include Body odor and bad breath (less with AGE), Gastrointestinal discomfort (heartburn, nausea, gas), Increased bleeding risk, Allergic reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Garlic and High Blood Pressure (Hypertension)?
            
        
        

            We rate the evidence as Grade A (Strong Evidence). This rating is based on 12 peer-reviewed studies with 550 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
            

        

        

    


    
    












    

        FDAに関する免責事項:
        これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。