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Grape Seed Extract pour High Blood Pressure (Hypertension)

B

Meta-analysis of 16 RCTs: systolic -6.08 mmHg. Greater effect in younger (<50) and obese participants. OPC standardization important for consistent results.

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            B

        

        

            
En conclusion

            
            
Meta-analysis of 16 RCTs: systolic -6.08 mmHg. Greater effect in younger (<50) and obese participants. OPC standardization important for consistent results.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
16

        
Études

    

    

        
810

        
Participants

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Note

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Posologies couramment utilisées

                

                    
                    

                        
general:

                        
100-300 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
150-300 mg/day standardized to 95% OPCs

                    

                    
                

                
                

                    Limite supérieure : Not formally established; up to 600 mg/day used in clinical trials
                

                
            

            

            

            
            

                Moment optimal de prise : With or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effets indésirables signalés

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild headache (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Dizziness (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea (rare)
                        
    • 
                        
                    

                

                

                
                

                    
Interactions connues

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may increase bleeding risk)
                        
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                            ●
                            Blood pressure medications (additive hypotensive effect)
                        
    • 
                        
                        
  • 
                            ●
                            Iron supplements (tannins may reduce iron absorption)
                        
    • 
                        
                    

                

                

                
                

                    

                        Apport maximal tolérable : Not formally established; up to 600 mg/day used in clinical trials
                    

                

                
            

            

                Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Grape Seed Extract help with High Blood Pressure (Hypertension)?
            
        
        

            Based on 16 studies with 810 participants, there is moderate evidence from clinical studies that Grape Seed Extract may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Grape Seed Extract should I take for High Blood Pressure (Hypertension)?
            
        
        

            Studies have used various dosages. A commonly studied range is 100-300 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Grape Seed Extract?
            
        
        

            Reported side effects may include Generally well-tolerated, Mild headache (rare), Dizziness (rare), Nausea (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Grape Seed Extract and High Blood Pressure (Hypertension)?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 16 peer-reviewed studies with 810 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Grape Seed Extract pour d'autres pathologies

                    

                        
                        
                            Endothelial Dysfunction
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

        Avertissement FDA:
        Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.