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Grape Seed Extract per High Blood Pressure (Hypertension)

B

Meta-analysis of 16 RCTs: systolic -6.08 mmHg. Greater effect in younger (<50) and obese participants. OPC standardization important for consistent results.

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            B

        

        

            
In sintesi

            
            
Meta-analysis of 16 RCTs: systolic -6.08 mmHg. Greater effect in younger (<50) and obese participants. OPC standardization important for consistent results.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
16

        
Studi

    

    

        
810

        
Partecipanti

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Grado

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosaggi di uso comune

                

                    
                    

                        
general:

                        
100-300 mg/day

                    

                    
                    

                        
bloodpressuresupport:

                        
150-300 mg/day standardized to 95% OPCs

                    

                    
                

                
                

                    Limite massimo: Not formally established; up to 600 mg/day used in clinical trials
                

                
            

            

            

            
            

                Momento migliore per l'assunzione: With or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effetti collaterali segnalati

                    
    
                        
                        
  • 
                            ⚠
                            Generally well-tolerated
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild headache (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Dizziness (rare)
                        
    • 
                        
                        
  • 
                            ⚠
                            Nausea (rare)
                        
    • 
                        
                    

                

                

                
                

                    
Interazioni note

                    
    
                        
                        
  • 
                            ●
                            Anticoagulants (may increase bleeding risk)
                        
    • 
                        
                        
  • 
                            ●
                            Blood pressure medications (additive hypotensive effect)
                        
    • 
                        
                        
  • 
                            ●
                            Iron supplements (tannins may reduce iron absorption)
                        
    • 
                        
                    

                

                

                
                

                    

                        Livello di assunzione massimo tollerabile: Not formally established; up to 600 mg/day used in clinical trials
                    

                

                
            

            

                Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Grape Seed Extract help with High Blood Pressure (Hypertension)?
            
        
        

            Based on 16 studies with 810 participants, there is moderate evidence from clinical studies that Grape Seed Extract may support High Blood Pressure (Hypertension) management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Grape Seed Extract should I take for High Blood Pressure (Hypertension)?
            
        
        

            Studies have used various dosages. A commonly studied range is 100-300 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Grape Seed Extract?
            
        
        

            Reported side effects may include Generally well-tolerated, Mild headache (rare), Dizziness (rare), Nausea (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Grape Seed Extract and High Blood Pressure (Hypertension)?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 16 peer-reviewed studies with 810 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Grape Seed Extract per altre condizioni

                    

                        
                        
                            Endothelial Dysfunction
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

        Avvertenza FDA:
        Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.